Antidotes Flashcards
Activated Charcoal
Name
Actidose
Activated Charcoal
Class
absorbent
Activated Charcoal
Description
Is a specially prepared charcoal that will absorb and bind toxins from the gastrointestinal tract
Activated Charcoal
Indications
acute ingested poisoning
Activated Charcoal
Precautions
administer only after emesis or in those cases where emesis is contraindicated
Activated Charcoal
Dosage/Route
1g/kg mixed with at least 6 to 8 oz of water, then PO or via NG tube
Narcan
Name
Naloxone
Narcan
Class
Narcotic Antagonist
Narcan
Description
Naloxone is a pure narcotic antagonist that blocks the effects of both natural and synthetic narcotics and may reverse respiratory depression
Narcan
Indications
Narcotic and synthetic narcotic overdose, coma of unknown origin
Narcan
Contraindications
Hypersensitivity to the drug, non-narcotic induced respiratory depression
Narcan
Precautions
Possible dependency (including newborns). It also has a half life that is shorter than that of most narcotics: hence patient may return to the overdose state
Romazicon
Name
Flumazenil
Romazicon
Class
Benzodiazepine Antagonist
Romazicon
Description
Flumazenil is a benzodiazepine antagonist used to reverse the sedative, recall and psychomotor effects of diazepam, midazolam and the other benzodiazepine
Romazicon
Indications
Respiratory depression secondary to benzodiazepines
Romazicon
Contraindications
hypersensitivity to flumazenil or benzodiazepines; those patients who take medication for status epilepticus or seizures; seizure-prone patients during labor and delivery; tricyclic antidepressant overdose
Romazicon
Precautions
Hepatic impairment, elderly, pregnancy, nursing mothers, head injury, alcohol and drug dependency and physical dependence on benzodiazepines
Romazicon
Doseage/Route
0.2mg IV over 30 seconds, up to 1mg