Antidotes Flashcards
1
Q
Acetaminophen
A
N-acetylcysteine (replenishes glutathione)
2
Q
AChE inhibitors (organophosphates)
A
Atropine followed by pralidoxime (bind to organophosphate-inactivated AChE)
3
Q
Amphetamines
A
NH4Cl (acidifes urine)
4
Q
Antimuscarinics, anticholinergics
A
Physostigmine (crosses BBB), control hyperthermia
5
Q
Benzos
A
Flumazenil
6
Q
Beta blockers
A
Glucagon
7
Q
Carbon monoxide
A
Oxygen
8
Q
Copper, arsenic, gold
A
Penicillamine
9
Q
Cyanide
A
Nitrites (oxidize hemoglobin to methemoglobin, which more avidly binds cyanide), thiosulfate, hydroxocobalamin
10
Q
Digitalis
A
Anti-dig Fab fragments
11
Q
Heparin
A
Protamine sulfate
12
Q
Iron
A
Deferoxamine, deferasirox
13
Q
Lead
A
EDTA, dimercaprol, succimer, pencillamine
14
Q
Mercury, arsenic, gold
A
Dimercaprol (BAL), succimer
15
Q
Methanol, ethyelene glycol (antifreeze)
A
Fomepizole > ethanol, dialysis
