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Pharmacology > Antidepressants & Stimulants > Flashcards

Antidepressants & Stimulants Flashcards

1
Q

Amitriptyline

A

TCA

Treats major depression

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2
Q

Amoxapine

A

TCA

Treats major depression

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3
Q

Imipramine

A

TCA

Treats major depression

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4
Q

Nortriptyline

A

TCA

Treats major depression

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5
Q

Citalopram

A

SSRI

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6
Q

Escitalopram

A

SSRI

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7
Q

Fluoxetine

A

SSRI
Demethylated to Norfluoxetine
Half life: up to 30 days

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8
Q

Sertraline

A

SSRI

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9
Q

Duloxetine

A

SNRI
Highly bound to plasma proteins
Metabolized by CYP1A2 and CYP2D6
Not used for patients with hepatic insufficiency

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10
Q

Venlafaxine

A

SNRI
Doesn’t bind to plasma proteins much
Metabolized by CYP2D6

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11
Q

Bupropion

A

Atypical antidepressant
Inhibits dopamine reuptake
Tx: bipolar disorder

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12
Q

Mirtazapine

A

Atypical antidepressant

Increases NE and serotonin release by blocking alpha2 receptors

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13
Q

Nefazodone

A

Atypical antidepressant

Inhibits reuptake of serotonin and blocks 5-HT2 receptors

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14
Q

Phenelzine

A

MAOI

Inhibits both A and B types

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15
Q

Selegiline

A

MAOI
Transdermal
MAO-B and MAO-A(at high conc)
Also used for Parkinson’s

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16
Q

Tranylcypromine

A

MAOI

Inhibits both A and B types

17
Q

Lithium

A

Used for bipolar disorder

18
Q

Carbamazepine

A

Bipolar disorder

Anticonvulsant

19
Q

Olanzapine

A

Antipsychotic for bipolar disorder

20
Q

Risperidone

A

Antipsychotic for bipolar disorder

21
Q

Valproic acid

A

Anticonvulsant for bipolar disorder

22
Q

Amphetamine

A

Psychomotor stimulant
“Adderall”
Easily abused and cheap

23
Q

Atomoxetine

A

NE reuptake inhibitor
NOT a psychostimulant
Not addictive
Tx: ADHD

24
Q

Dextro-amphetamine

A 
Amphetamine
Psychomotor stimulant (combats fatigue and produces euphoria)
Prevents narcolepsy
Tx: ADHD
Oral
25
Q

Methylphenidate

A 
Amphetamine
"Ritalin"
Prevents narcolepsy
Tx: ADHD
Oral
26
Q

Modafinil

A

Tx: narcolepsy

Mechanism unclear

Pharmacology (10 decks)

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