Antidepressants

Question 1

What is first line antidepressant

Answer 1

Fluoxetine

Question 2

Which one is useful post MI

Answer 2

Sertraline

Question 3

What’s the most common side effect

Answer 3

GI symptoms

Question 4

What is the main GI risk with antidepressants

Answer 4

GI bleeding - if taking NSAID should coprescribe a PPI

Question 5

What are citalopram and escitalopram associated with

Answer 5

QT prolongation

Question 6

Coprescrobing SSRIS and warfarin and heparin

Answer 6

Should be avoided use mirtazepine instead

Question 7

Using triptans or MAOI with SSRIS

Answer 7

Increased risk of serotonin syndrome

Question 8

When should you review a patient who has just started an antidepressant

Answer 8

After 2 weeks, 1 if increased risk do suicide

Question 9

Apart from fluoxetine how long does it usually take to stop an SSRI

Answer 9

Graded reduction over 4 weeks

Question 10

What risks do SSRIs have in pregnancy

Answer 10

First trimester - heart defects
Third - PPH

Paroxetine has a risk of congenital malformations particularly in the first trimester