Antidepressants Flashcards
How can the reabsorption of noradrenaline be altered to decrease depression?
Noradrenaline uptake inhibitors and tricyclic antidepressants can prevent noradrenaline transporters from reabsorbing noradrenaline, increasing levels within the body
What is the process of noradrenaline release?
Noradrenaline is released by noradrenergic nerve cells, then binds to post-synaptic adrenoreceptors. noradrenaline transporters then reabsorb leftover noradrenaline into the cell along before it is broken down by MAO-A enzyme
How can the breakdown of noradrenaline and serotonin be altered to decrease depression?
monoamine oxidase inhibitors (MAOIs) prevent the breakdown of noradrenaline and serotonin via the enzyme MAO-A, therefore increasing levels within the body
What is the process of serotonin release?
Serotonin is released by serotonergic nerve cells, then binds to postsynaptic serotonin receptors. serotonin transporters reabsorb leftover serotonin into the cell along before it is broken down by MAO-A enzyme
How can the reabsorption of serotonin be altered to decrease depression?
Serotonin reuptake inhibitors and tri-cyclic antidepressants can prevent serotonin transporters from reabsorbing serotonin, increasing levels within the body