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Rheumatology CBD > Antibodies (backwards & forwards) > Flashcards

Antibodies (backwards & forwards) Flashcards

1
Q

Anti-cyclic citrullinated peptide (anti-CCP)

A

Rheumatoid arthritis

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2
Q

Anti-centromere

A

CREST syndrome (limited systemic sclerosis)

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3
Q

Anti-Jo-1

type of anti-synthetase

A

Polymyositis / dermatomyositis

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4
Q

Anti-Scl70

anti-DNA topoisomerase

A

Systemic sclerosis, diffuse

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5
Q

Anti-RNA polymerase

anti-U3 RNP

A

Systemic sclerosis, esp with renal crisis

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6
Q

Anti-U1 RNP

anti-RNP not otherwise specified

A

Mixed connective tissue disease

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7
Q

Anti-Smith (anti-Sm)

A

Lupus

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8
Q

Anti-double-stranded DNA (anti-dsDNA)

A

Lupus

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9
Q

Anti-nuclear (ANA)

A

Lupus and many other rheumatic diseases

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10
Q

Anti-SSA (= anti-Ro)

Anti-SSB (= anti-La)

A

Sjogren syndrome, neonatal lupus, subcutaneous lupus

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11
Q

Anti-myeloperoxidase

(= perinuclear anti-neutrophil cytoplasmic, P-ANCA

A

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg Strauss)

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12
Q

Anti-proteinase-3 (= diffuse cytoplasmic

anti-neutrophil cytoplasmic, C-ANCA

A

Granulomatosis with polyangiitis (Wegener’s)

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13
Q

Granulomatosis with polyangiitis (Wegener’s)

A

C-ANCA, anti-proteinase-3, diffuse ANCA

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14
Q

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg Strauss)

A

Anti-myeloperoxidase

(= perinuclear anti-neutrophil cytoplasmic, P-ANCA

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15
Q

Sjogren syndrome, neonatal lupus, subcutaneous lupus

A

Anti-SSB (= anti-La), Anti-SSA (= anti-Ro)

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16
Q

Lupus and many other rheumatic diseases

A

Anti-nuclear (ANA)

17
Q

Lupus

A

anti-dsDNA, anti-Sm

18
Q

Mixed connective tissue disease

A

Anti-U1 RNP (anti-RNP not otherwise specified)

19
Q

Systemic sclerosis, esp with renal crisis

A

Anti-RNA polymerase

anti-U3 RNP

20
Q

Systemic sclerosis, diffuse

A

Anti-Scl70

anti-DNA topoisomerase

21
Q

Polymyositis / dermatomyositis

A

Anti-Jo-1

type of anti-synthetase

22
Q

CREST syndrome (limited systemic sclerosis)

A

Anti-centromere

23
Q

Rheumatoid Arthritis

A

Anti-cyclic citrullinated peptide (anti-CCP)

Rheumatology CBD (7 decks)

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