Antibiotics

Question 1

What are the three ways in which antibiotics work ?

Answer 1

Inhibit cell wall
Inhibit protein synthesis
Inhibit nuclear acid synthesis

Question 2

What are the types of antibiotic which inhibits the cell wall?

Answer 2

B lactams

Glycopeptides

Question 3

Examples of B lactams

Answer 3

Penicilin and cephalosporin

Question 4

What kind of bacteria do B lactams work on ?

Answer 4

Gram +

Question 5

What does B lactams do to bacteria ?

Answer 5

kill them

Question 6

What do B lactams do to the cell wall?

Answer 6

Inhibit peptidoglycans

Question 7

Examples of glycopeptides

Answer 7

Vancomycin IV

Teicoplanin Single does parental

Question 8

What kind of bacteria do glycopeptides work on ?

Answer 8

Gram +

Question 9

What does glycopeptides do to bacteria ?

Answer 9

kill them

Question 10

What do glycopeptides do to the cell wall?

Answer 10

Inhibit assembly of peptidoglycan precursors

Question 11

What are the antibiotics that inhibit protein synthesis ?

Answer 11

Aminoglycosides 
Macrolides
Tetracyclines 
Oxazolidinones 
Cyclic lipopeptide strong

Question 12

Examples of Aminoglycosides

Answer 12

Gentamicin (cheap and effective)

Question 13

What kind of bacteria do Aminoglycosides work on ?

Answer 13

Gram -

Question 14

What does Aminoglycosides do to bacteria ?

Answer 14

Kill them

Question 15

How do Aminoglycosides work?

Answer 15

Cause misreading of RNA and premature termination

Question 16

Examples of Macrolides

Answer 16

Erythromycin
Clarithromycin
Azithromycin (Single dose)

Question 17

What kind of bacteria do Macrolides work on ?

Answer 17

Gram + (useful alternative to penicillin)

Question 18

What does do Macrolides to bacteria ?

Answer 18

Kill or inhibit

Question 19

How do Macrolides work?

Answer 19

prevent adding of amino acids and inhibit ribosomal translation

Question 20

What kind of bacteria do Tetracyclines work on?

Answer 20

Gram +

Question 21

what does Tetracyclines do to bacteria?

Answer 21

Inhibit

Question 22

How do Tetracyclines work?

Answer 22

prevent tRNA from binding to the ribosomes

Question 23

Examples of Oxazolidinones

Answer 23

Linezolid

Question 24

What kind of bacteria do Oxazolidinones work on?

Answer 24

Gram +

Question 25

What do Oxazolidinones do bacteria ?

Answer 25

Kill or inibit

Question 26

How do Oxazolidinones work?

Answer 26

Prevents the formation of the initiation complex.

Question 27

Examples of cyclin lipopeptide strong

Answer 27

Daptomycin

Question 28

What kind of bacteria do cyclin lipopeptide strong work on?

Answer 28

Gram +

Question 29

What do cyclin lipopeptide strong do to bacteria?

Answer 29

Kill them

Question 30

How do cyclin lipopeptide strong work ?

Answer 30

Creates holes that leak ions

Question 31

What are the classes of antibiotic which inhibit nucellar acid synthesis?

Answer 31

Inhibition purine synthesis | Fluoroquinolones

Question 32

Examples of Fluoroquinolones

Answer 32

Ciprofloxacin and levofloxacin

Question 33

What kind of bacteria do Fluoroquinolones work on?

Answer 33

Gram -

Question 34

What do Fluoroquinolones do to bacteria?

Answer 34

kill them

Question 35

How do Fluoroquinolones work?

Answer 35

They inhibit DNA synthesis.

Question 36

Examples of Inhibition (different steps) in purine synthesis ?

Answer 36

trimethoprim

Question 37

What do Inhibition (different steps) in purine synthesis do to bacteria ?

Answer 37

Inhibit them

Question 38

Which antibiotics work on gram negative?

Answer 38

Aminoglycosides | Fluoroquinolones

Question 39

What antibiotics inhibit bacteria?

Answer 39

Inhibition (different steps) in purine synthesis Oxazolidinones Tetracyclines Macrolides