Antibiotic Clinical Applications Flashcards

1
Q

Uncomplicated Skin and Soft Tissue Infections

A

Penicillin (ampicillin)

1st Generation Cephalosporin (cephalexin)

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2
Q

Complicated skin and soft tissue infections

A

pencillin + lactamase inhibitor

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3
Q

MRSA

A

vancomycin, linezolid, daptomycin

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4
Q

osteomyelitis

A

vancomycin

cephalosporin (ceftriaxone or cefepime)

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5
Q

surgeries (bone and joint infections)

A

penicillin + lactamase inhibitor

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6
Q

Septic arthritis

A

Ceftriaxone

if MRSA: vancomycin, lenezolid, daptomycin

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7
Q

Prosthetic joint (infection)

A

Rifampin

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8
Q

Acute Sinusitis

A

penicillin + lactamase inhibitor

Amoxicillin + clavulanate

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9
Q

Pharyngitis

A

Penicillin

Amoxicillin

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10
Q

Community-acquired pneumonia: ambulatory

A

Macrolide

erythromycin, azithromycin, clarithromycin

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11
Q

Community-acquired pneumonia: hospitalization

A

B-lactam + macrolide

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12
Q

Community-acquired / Hospital-acquired pneumonia: MRSA

A

vancomycin or linezolid

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13
Q

Hospital-acquired pneumonia

A

Ceftriaxone

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14
Q

Uncomplicated UTI: Cystitis

A

Trimethoprim / Sulfamethoxazole (TMP-SMX)

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15
Q

Uncomplicated UTI: pyelonephritis

A

Trimethoprim / Sulfamethoxazole (TMP-SMX)

Fluoroquinolone

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16
Q

Complicated UTI

A

Fluoroquinolone

Trimethoprim / Sulfamethoxazole (TMP-SMX)

17
Q

Prostatis

A

Fluoroquinolone

Trimethoprim / Sulfamethoxazole (TMP-SMX)

18
Q

Intra-abdominal infections

A

Ticarcillin + clavulanate

19
Q

C. Difficile infection

A

Moderate: metronidazole

Severe: vancomycin

20
Q

Community-acquired bacterial meningitis

A

Ceftriaxone

Cefotaxime + vancomycin

21
Q

Neonatal meningitis

A

Ampicillin + cephalosporin +/- gentamicin

22
Q

Sepsis Syndrome

A

3rd or 4th generation Cephalosporin

Cefepime +/- vancomycin

23
Q

Endocarditis

A

ceftriaxone + vancomycin

24
Q

Fever + Neutropenia

A

Ciprofloxacin + amoxicillin/clavulanate

25
Q

Enterocci Multi-drug resistance

A

Linezolid, daptomycin, tigecycline

26
Q

Gram (-) Multi-drug resistant bacteria

A

Extended spectrum Beta-lactamses (ESBL) Bacteria: imipenem or meropenem

Carbapenemase bacteria: Polymyxin B or Tigecycline