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Pharma > Antibacterials > Flashcards

Antibacterials Flashcards

1
Q

“kills”
cell wall synthesis inhibitor
Narrow

A

Cidals

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2
Q

“inhibits”
protein synthesis inhibitor
broad spectrum

A

Satics

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3
Q

inhibits transpeptidase

A

pinicillin

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4
Q

1st line antipseudomonals

A

Ceftazidime

Ciprofloxacin

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5
Q

Causes Interstitial nephritis

A

MEthicillin

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6
Q

Penicillinase resistant PCNs

A

Oxacillin
Nafcillin
Dicloxacillin

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7
Q

This is combined intravenously with imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect.

A

Cilastatin

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8
Q

Inhibits peptidoglycan polymerization by inhibiting D-ala Dala portion. Used for all Gram (+), for treatment of C. difficile.

A

Vancomycin

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9
Q

Side effect of Vancomycin

A

Red man syndrome

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10
Q

Drugs affecting 30s and 50s subunits

A 
buy AT 30, CELL at 50
30s
Aminoglycosides
Tetracyclins
50s
Chloramphenicol
Erythromycin
Linezolid
cLindamycin
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11
Q

“mycin”

A

Animoglycosides

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12
Q

Inhibits initiation complex

A

Aminoglycosides

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13
Q

Inhibits amino acid incorporation

A

Tetracylcine

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14
Q

Inhibits peptic bond formation

A

Chloramphenicol

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15
Q

Inhibits translocation

A

Clindamycin

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16
Q

Causes destruction of Teeth and bones

A

“TEETHracycline”

17
Q

Causes Aplastic Anemia and Gray baby syndrome

A

Chloramphenicol

18
Q

Enzyme needed for billirubin conjugation. Lacking in babies with gray baby syndrome.

A

UDP glucoronyl transferase

19
Q

Used for Typhoid, meningitis, anaerobes, rickets and brucellosis

A

chloramphenicol

20
Q

alternative of penicillin allergy

A

erythromycin

21
Q

a macrolide that inhibits CypP450

A

erythomycin

22
Q

first line for severe anaerobic infections and aspiration pneumonia

A

Clindamycin

23
Q

Inhibits DNA gyrase/tropoisomerase/ NUCLEIC ACID synthesis

A

Fluoroquinolones

24
Q

fluoroquinolone drugs ends with?

A

“Floxacin”

25
Q

Causes Cartilage erosion, tendon rupture(achilles tendon)

A

fluoroquinolone

26
Q

Drugs responsible for inhibition of Folic acid synthesis

A

Sulfonamides and Trimetrhoprim

27
Q

Sulfo+Trimethroprim =?

A

Cotraimoxazole

28
Q

Treats MArrow poorly?

A

Trimethroprim

29
Q

Inhibits dihydropteroate synthase

A

Sulfonamides, dapsone

30
Q

Drugs that cause SJS

A

Sulfonamide (30%): fansider, sulfodiazine, TMP SMX

Antigoagulants: Carbamazepines, phenobarb, phenytoin

31
Q

First line for Pneumocystis infection

A

Cotrimoxazole

Pharma (17 decks)

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