Antibacterial sections

Question 1

anthrax treatment…

Answer 1

cipro (or doxy in patients over 12)
combined with one or two other antibacterials

when sensitivities become known change to a single antibacterial

Question 2

how long to treat anthrax for

Answer 2

60 days if GI or aerosol - because germination may be delayed

if cutaneous treat for 7 days
14 days if cutaneous with systemic features

Question 3

3 drugs recommend for leporasy

Answer 3

dapsone
rifampicin
clodazimine

Question 4

what do use for pain in leporasy - what might this indicate

Answer 4

prednisolone

pain is the herald of permanent nerve damage

Question 5

what 3 antibacterials might we use for lyme disease

Answer 5

doxy
amox
cefuroxime

Question 6

is linezolid active against gram neg organisms

Answer 6

no

Question 7

what would you use to treat a UTI caused by MRSA

Answer 7

tetracycline

Question 8

ethambutol is a treatment for …… and what is the particular risk of it

Answer 8

TB
ocular toxicity (especially in renal failure) stopping drug nearly always results in recovery of eyesight loss

Question 9

what TB drug increases risk of peripheral neuropathy and what drug do we use to prevent it

Answer 9

isoniazid

prevent with pyridoxine in pt at high risk
- includes diabetes HIV CKD preg, malnutirtion, ETOH