Antiarrhythmics

Question 1

Atropine May cause bradycardia

Answer 1

True. In low doses can cause a bradycardia initially due to Bezold-Jarisch reflex.

Question 2

Atropine May cause ataxia

Answer 2

True. Can cross blood-brain barrier and cause central anticholinergic syndrome.

Question 3

Atropine Reduces physiological dead space

Answer 3

False. Increases due to bronchodilation.

Question 4

Atropine Has equal muscarinic and nicotinic effects

Answer 4

False. Antagonises acetylcholine at muscarinic receptors and only has a minimal effect on nicotinic at higher doses.

Question 5

Atropine Can precipitate urinary retention

Answer 5

True

Question 6

Isoprenaline can be used in the management of complete heart block

Answer 6

True. Until pacing can be arranged.

Question 7

Isoprenaline causes hypertension

Answer 7

False. Due to β2 action.

Question 8

Dopamine can be given orally

Answer 8

False. Is ineffective.

Question 9

Aminophylline is arrhythmogenic

Answer 9

True. Can precipitate arrhythmias including ventricular fibrillation.

Question 10

Atropine is given during PEA arrest

Answer 10

False. As of 2010 ALS guidelines, it is no longer indicated.

Question 11

Amiodarone:

Increases opening times of myocardial potassium channels

Answer 11

False. Blocks potassium channels.

Question 12

Amiodarone:

Slows rate of repolarization

Answer 12

True. Also increases refactory period.

Question 13

Amiodarone:

Reduces action of digoxin

Answer 13

False. By displacement from plasma proteins.

Question 14

Amiodarone:

Causes corneal deposits

Answer 14

True. Seen in almost all patients.

Question 15

Amiodarone:

Slows conduction through ventricular myocardium

Answer 15

False. Affects atrioventricular node conduction.

Question 16

Regarding antiarrhythmic drugs:

Amiodarone enhances conduction through the bundle of His

Answer 16

False. Amiodarone has no effects on the bundle of His.

Question 17

Regarding antiarrhythmic drugs:

Flecainide suppresses ventricular ectopics

Answer 17

True

Question 18

Regarding antiarrhythmic drugs:

Magnesium is not useful in AF and torsades de pointes

Answer 18

False. It is first line treatment of torsades de pointes.

Question 19

Regarding antiarrhythmic drugs:

Adenosine can differentiate supraventricular from ventricular arrhythmias

Answer 19

True

Question 20

Regarding antiarrhythmic drugs:

Calcium channel antagonists are used in the management of ventricular tachycardia

Answer 20

False. Used in the management of supra-ventricular tachycardias.

Question 21

Adenosine:

Is a naturally occurring substance

Answer 21

True. It is a naturally occurring purine nucleoside

Question 22

Adenosine:

Is given orally

Answer 22

False. Is given as a rapid IV bolus.

Question 23

Adenosine:

Can cause severe bradycardia

Answer 23

True. Causes transient heart block.

Question 24

Adenosine:

Has cellular protective effects during hypoxia or ischaemia

Answer 24

True

Question 25

Adenosine:

Can cause brochospasm

Answer 25

True. In susceptible patents.

Question 26

The following are features of digoxin toxicity:

Headache

Answer 26

True

Question 27

The following are features of digoxin toxicity:

Abdominal pain

Answer 27

True

Question 28

The following are features of digoxin toxicity:

Convulsions

Answer 28

True

Question 29

The following are features of digoxin toxicity:

Atrial fibrillation

Answer 29

False

Question 30

The following are features of digoxin toxicity:

Gynaecomastia

Answer 30

True