Antiarrhythmics Flashcards
Atropine May cause bradycardia
True. In low doses can cause a bradycardia initially due to Bezold-Jarisch reflex.
Atropine May cause ataxia
True. Can cross blood-brain barrier and cause central anticholinergic syndrome.
Atropine Reduces physiological dead space
False. Increases due to bronchodilation.
Atropine Has equal muscarinic and nicotinic effects
False. Antagonises acetylcholine at muscarinic receptors and only has a minimal effect on nicotinic at higher doses.
Atropine Can precipitate urinary retention
True
Isoprenaline can be used in the management of complete heart block
True. Until pacing can be arranged.
Isoprenaline causes hypertension
False. Due to β2 action.
Dopamine can be given orally
False. Is ineffective.
Aminophylline is arrhythmogenic
True. Can precipitate arrhythmias including ventricular fibrillation.
Atropine is given during PEA arrest
False. As of 2010 ALS guidelines, it is no longer indicated.
Amiodarone:
Increases opening times of myocardial potassium channels
False. Blocks potassium channels.
Amiodarone:
Slows rate of repolarization
True. Also increases refactory period.
Amiodarone:
Reduces action of digoxin
False. By displacement from plasma proteins.
Amiodarone:
Causes corneal deposits
True. Seen in almost all patients.
Amiodarone:
Slows conduction through ventricular myocardium
False. Affects atrioventricular node conduction.
Regarding antiarrhythmic drugs:
Amiodarone enhances conduction through the bundle of His
False. Amiodarone has no effects on the bundle of His.
Regarding antiarrhythmic drugs:
Flecainide suppresses ventricular ectopics
True
Regarding antiarrhythmic drugs:
Magnesium is not useful in AF and torsades de pointes
False. It is first line treatment of torsades de pointes.
Regarding antiarrhythmic drugs:
Adenosine can differentiate supraventricular from ventricular arrhythmias
True
Regarding antiarrhythmic drugs:
Calcium channel antagonists are used in the management of ventricular tachycardia
False. Used in the management of supra-ventricular tachycardias.
Adenosine:
Is a naturally occurring substance
True. It is a naturally occurring purine nucleoside
Adenosine:
Is given orally
False. Is given as a rapid IV bolus.
Adenosine:
Can cause severe bradycardia
True. Causes transient heart block.
Adenosine:
Has cellular protective effects during hypoxia or ischaemia
True
Adenosine:
Can cause brochospasm
True. In susceptible patents.
The following are features of digoxin toxicity:
Headache
True
The following are features of digoxin toxicity:
Abdominal pain
True
The following are features of digoxin toxicity:
Convulsions
True
The following are features of digoxin toxicity:
Atrial fibrillation
False
The following are features of digoxin toxicity:
Gynaecomastia
True
