Antiarrhythmias Flashcards
class I blocks ____
Na channels
class II blocks ____
beta receptors
class III blocks ____
K efflux
class IV blocks ____
Ca channel
What class? Lidocaine
IB
What class? Flecainide
IC
What class? Amiodarone
III
What class? Diltiazem
IV
What class? Metoprolol
II
What class? Quinidine
IA
What class? Mexiletine
IB
What class? Sotalol
III
What class? Verapamil
IV
What class? Procainamide
IA
What class? Dronedarone
III
What class? Ibutalide
III
Which classes have risk of long QT syndrome?
IA, III
Contraindicated in WPW
Any rate control drug Class II (beta), IV (Ca)
Used to treat inherited long QT syndrome, the Na channel mutation
Mexiletine (IB)
Rhythm control for VT or SVT if there is no history of MI/ischemic disease
Flecainide (IC)
Blocking _____ increases APD
K+ efflux
Blocking _____ and ______ increases ERP
Na channels
Ca channels
First line rhythm control for VT in structurally abnormal hearts (post MI)
Amiodarone
after cardioversion
Causes the longest ERP
Flecainide (IC)
First line for Afib rhythm control
Amiodarone
Rhythm control for patients with ICD
Sotalol
Use for acute chemical cardioversion in Afib
IV Ibutalide (III)
2nd line rhythm control for VT post-MI (or hx ischemic disease)
IV Lidocaine (IB)
Use for re-entry tachycardias
Class I
Decreasing conduction velocity will ______ERP
Increase
Contraindicated in CHF
Class IV (Verapamil, diltiazem)
Rate control classes
II & IV
even rate
Rhythm control classes
I & III
odd rhythm
inhibits Na/K ATPase
increases vagal activity
Digoxin
Consider for Afib in CHF
Digoxin
Increases K efflux, hyper polarizing the cell
Adenosine
opposite MOA as Class III
Use for AV-node dependent narrow complex tachycardia
IV Adenosine
Use for Afib
verapamil
diltiazem
metoprolol
(II & IV)
Only treats VT
Class IB (Lidocaine)
Only treats SVT
Class II & IV
Digoxin
Adenosine
(rate control)
