Anti protozoals Flashcards
Treatment for active infections
coccidiocides
Treatment to prevent infections
coccidiostats
Coccidiocides
Sulfonamides (primarily sulfadimethoxine(albon)) and Furazolidone (banned in food animals)
Coccidiostats
ionophores (monensin (coban, rumensin), lasalocid (bovatec)), used in cattle/poultry/smallruminants; amprolium (corid), approved in cattle/poultry, extra-label use in small ruminants/dogs; dexoquinate; ponazuril
Toxoplasmosis treatment
Clindamycin (prefered in cats), pyrimethamine + sulfadiazine
Balantidiasis (Balantidium coil) treatment
Tetracyclines drug of choice; metronidazole used outside of food animals but less consistent
Equine protozoal myelitis (EPM)
Pyrimethamine + sulfadiazine; fasting important, teratogenic; ponazuril, feeding with cornoil increases bioavailability
Giardiasis
Fendendazole (most common; metronidazole; furazolidone; nitazoxanide
Trichomonads
Metronidazole; Ronidazole; Clioquinol
Babesiosis
Imidocarb diproprionate (Imizol), pretreatment with atrophine important. Works better against B. canis; Atovaquone and azithromycin can be used to treat carrier state
Neosporosis
Clindamycin (same as Toxo); NeoGuard used for prevention in cattle
Cryptosporidiosis
Azithromycin is primary treatment, Nitozoxanide sometimes used
Leishmaniasis
Pentamidine isethionate (approved for humans); Allopurinol (used for 24 months)
Feline cytauxzoon
Atovaquone and Azithromycin; poor success rates (60% in one study)
Diseases with no treatment
Chagas; Trichomoniasis (in cattle); Histomoniasis (turkies)