Anti-Fungal Part 1 Flashcards

1
Q

Discovered Trichophyton schoenleinii

A

Schönlein and Gruby

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2
Q

Discovered C. albicans

A

Bernhard Von Langenbec

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3
Q

Topical agents for dermatophytosis

A

Fatty acids

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4
Q

SAR of Fatty acids

A

higher molecular weight members have the advantage of having lower volatility

Structure similar to sebum, a natural antifungal

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5
Q

Sodium and calcium propionates

Uses: preservative, for dermatomycosis

A

Propionic acid

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6
Q

Found in coconut and palm oil

Prepared from caprylic acid

A

Sodium Caprylate

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7
Q

Used as topical fungicide

Astringency of zinc decreases inflammation and wetness

A

Zinc Caprylate

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8
Q

Fungicide on adhesive tape

A

Zinc Propionate

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9
Q

Iupac of Undecylenic acid

A

10-Undecenoic acid

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10
Q

The primary fungicide for diaper rash

A

Sodium undecylenate

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11
Q

Destructive distillation of castor oil (Decenex ®, Cruex ®)

A

Undecylenic acid

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12
Q

Fungicidal properties are due to acetic acid formation, action is self-limiting because esterase are inactivated below a pH of 4

A

Triacetin (Enzactin, Fungacetin)

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13
Q

Antiseptic and keratolytic Commonly combined with benzoic acid to form an ointment

A

Salicylic acid

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14
Q

This ointment contains 6% benzoic acid and 6% salicylic acid in a petrolatum base

A

Whitfield’s ointment

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