anti-arrhythmics Flashcards
class IA
- definition
- what do they do to APD
- what do they do to ERP
- moderate Na channel blocker–moderate reduction in phase 0 slope
- increase
- increase
class IB
- definition
- what do they do to APD
- what do they do to ERP
- weak Na channel blocker
- small reduction in phase 0 slope
- reduce ADP
- decrease ERP
class IC
- definition
- what do they do to APD
- what do they do to ERP
- strong Na channel blocker
- large reduction in phase 0 slope
- no effect on APD
- no effect on ERP
class II
beta blckers
class III
- definition
- what do they do to APD
- what do they do to ERP
K channelk blocker
delay APD
increase ERP
class IV
- definition
- what do they do to APD
- what do they do to ERP
- Ca channel blocker
most effective at SA and AV node
reduce rate and conduction
Procainamide
- class
- Use
IA
most atrial and ventricular arrhythmias
Lidocaine
- class
- use
IB
terminates VT and prevents VF after cardioversion
Flecainide
- class
- use
IC
SVT in patients w/ normal heart
Class II use
atrial arrhythmia and prevention of recurrent infarction and sudden death
Amiodarone
- class
- use
III
serious ventricular arrhythmias and supraventricular arrhythmias
Dofetilide
- class
- use
III
maintenance or restoration of sinus rhythm in Afib
Verapamil
- class
- use
IV–CCB
SVT, HTN, Angina
what’s caveat with Class III
can increase QT and facilitate EADs leading to PMVT
which is the only antiarrhythmic that has ever been shown to improve mortality in post infarct patient?
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