anti-arrhythmic drugs Flashcards
1
Q
What are the types of anti-arrhythmic drugs? Name an example for each.
A
- Type 1a: Na+ channel blocker
- Procainamide - Type 1b: Na+ channel blocker
- Lidocaine - Type 1c: Na+ channel blocker
- Flecainide - Type 2: Beta blocker
- Metoprolol, Propanolol - Type 3: K+ channel blocker
- Amiodarone - Type 4: Calcium channel blocker
- Verapamil, Diltiazem
2
Q
Procainamide will…
A
Slows phase 0 depolarisation
3
Q
Lidocaine will…
A
Shorten Phase 3 repolarisation and APD
4
Q
Flecainide will…
A
Slows phase 0 depolarisation
5
Q
Metoprolol/Propanolol will…
A
Suppress phase 4 depolarisation
6
Q
Amiodarone will…
A
Prolong phase 3 repolarisation
7
Q
Verapamil/Diltiazem will…
A
Prolong action potential
8
Q
Effect of Procainamide on ERP
A
increases
9
Q
Effect of Lidocaine on ERP
A
unchanged
10
Q
Effect of Flecainide on ERP
A
unchanged
11
Q
Effect of metaprolol/propanolol on ERP
A
unchanged
12
Q
Effect of Amiodarone on ERP
A
increases
13
Q
Effect of Verapamil/Diltiazem on ERP
A
increases
