Anterior Uveitis Flashcards
Anterior uveitis is the inflammation of
Pars plicata and/or the iris.
idiopathic in __% of cases
50
Etiology/associations
50% idiopathic Post op Trauma Autoimmune- SLE, JIA, IBD, ankylosing spondylitis. HLA B27 positive Systemic infection- Herpes simplex or zoster, TB. Inflammation elsewhere in globe Anterior segment ischemia Retinal detachment Lens or drug induced. Cancer
Laterality
Systemic disease usually causes bilateral.
Exception- herpes usually unilateral.
Symptoms
Red eye Eye pain Tearing Photophobia Blurred vision
Signs
Injection of the conj and/or around the limbus (ciliary flush, circumlimbal flush)
AC rxn- WBC in AC. If severe, hypopyon can form.
Flare in AC (protein)
Ciliary flush
KP
Busacca/Koeppe nodules
PAS or PS
Pupillary mitosis
Low IOP in acute phase, High in chronic phase due to inflammatory disease obstructing TM or steroids.
Iris atrophy
ciliary flush, circumlimbal flush
Injection of the conj and or around the limbus
Keratic precipitates (KP)
WBCs on the K endothelium.
Fine KPs
Small, punctate, white WBCs on the K endothelium
Mutton Fat KPs
Large, greasy, yellow WBCs on the K endothelium. Typically inferior in arlt’s triangle.
Arlt’s triangle
Characteristic of granulatomous infection. Triangle inferior K endothelium
Busacca/Koeppe nodules
WBCs on the iris.
Busacca- mid periphery
Koeppe nodules keep to the pupillary margin
Peripheral anterior synechia (PAS)
Peripheral iris stuck to peripheral cornea
Posterior synechia (PS)
Iris pupillary zone stuck to the anterior lens.
How does IOP changed based on acute or chronic uveitis?
Acute- Lower IOP. (higher if herpetic etiology)
Chronic- Higher IOP. Due to inflammatory debris obstructing the TM or use of steroids.