ANS Receptors Flashcards

1
Q

Alpha 1 receptor type

A

Gq

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2
Q

Alpha 2 receptor type

A

Gi

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3
Q

Beta (1,2,3) receptor type

A

Gs

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4
Q

ACh- Nicotinic receptor type

A

Ion channels

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5
Q

Muscarinic 1,3,5 receptor type

A

Gq

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6
Q

Muscarinic 2, 4 receptor type

A

Gi

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7
Q

Dopamine 1 receptor type

A

Gs
Postsynaptic

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8
Q

Dopamine 2 receptor type

A

Gi
Presynaptic

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9
Q

Vasopressin 1 receptor type

A

Gq
Vasculature

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10
Q

Vasopressin 2 receptor type

A

Gs
Renal tubules

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11
Q

Histamine 1 receptor type

A

Gq

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12
Q

Histamine 2 receptor type

A

Gs

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13
Q

Beta-1 effects

A

Positive inotropy, chronotropy, and dromotropy

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14
Q

Beta 2 effects

A

Bronchodilation
Bladder sphincter contraction
Increased renin secretion
Vasodilation (skeletal muscle)

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15
Q

Alpha-1 effects

A

Vasoconstriction (GIT, skin)
Sphincter contraction (GIT, urinary tract)
Increase sweating
Decrease pancreatic activity
Increase renin secretion
Pupil dilation

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16
Q

M2 effects

A

Negative inotropic, chronotropic, and dromotropic effects

17
Q

M3 effects

A

Bronchoconstriction
Increase pulmonary secretions
Increase GIT activity (motility, sphincter relaxation, gland secretion)
Increase salivation, lacrimation, pancreatic activity
Bladder sphincter relaxation
Pupil constriction

18
Q

M1 effects

A

Increase salivation, lacrimation, and pancreatic activity

19
Q

Arterial vasoconstriction

A

Alpha 1> alpha 2

20
Q

Venous vasoconstriction

A

Alpha 2> alpha 1

21
Q

Venodilation

A

Beta 2

22
Q

Coronary vasoconstriction

A

Alpha 1 and 2

23
Q

Coronary vasodilation

A

B2
DA1

24
Q

Skeletal muscle vasoconstriction

A

Alpha 1

25
Q

Skeletal muscle vasodilation

A

Beta 2
M3

26
Q

Cerebral vasoconstriction

A

M1

27
Q

Cerebral vasodilation

A

M2
M5- formation of NO

28
Q

Mydriasis

A

Alpha 1

29
Q

Miosis

A

M3
M2

30
Q

Aqueous humor secretion

A

Beta-1

31
Q

Decreased insulin secretion

A

Alpha-2

32
Q

Increased insulin secretion

A

M3

33
Q

Glycogenolysis and gluconeogenesis

A

Alpha 1
Beta 2

34
Q

Increased renin release

A

Beta-1
DA-1

35
Q

Diuresis

A

Alpha-2

36
Q

Alpha-2 nervous system effects and receptor locations

A

Decrease SNS tone (medulla)
Increase PNS tone (vagus nerve)
Sedation, hypnosis (locus coeruleus)
Analgesia (dorsal horn of spinal cord)
Antishivering

37
Q

V1 cellular receptor

A

Mediates cardiovascular effects such as increased SVR

38
Q

V2 cellular receptor

A

Primarily function in the kidney as an antidiuretic hormone

39
Q

V3 cellular receptor

A

Found in pituitary gland and modulate autocoids