Animal A&P Test 1 Flashcards
Cytoplasm
-Inner substance of the cell, not including the nucleus
-Composed of cytosol, cytoskeleton and organelles
Cytosol
Viscous liquid with dissolved electrolytes, amino acids, sugars, and proteins (mostly enzymes)
Cytoskeleton
-Flexible fibrous structure
-Can change depending on cell’s activities
-Gives support and shape
-Allows movement
-Provides directions for metabolic activity
-Anchors organelles
Mitochondria
-Powerhouse of the cell
-Respiration occurs here
-Double membrane, site of ATP production
-Contain RNA and DNA
Endoplasmic Reticulum
-Flattened membranes stacked on each other
-Membrane is single lipid bilayer
-Large surface area
-Rough ER- Ribosomes attached; modifies proteins produced by the ribosomes
-Smooth ER- functions in synthesis and storage of lipids
Ribosome
-Most numerous organelle
-Composed of two subunits and rRNA
-Manufactures proteins by assembling amino acids
Golgi apparatus
-Composed of flattened membranes
-Modification, packing, and distribution center for intracellular products and secreted products
Lysosome
-Type of specialized vesicle formed by the golgi apparatus
-Contains hydrolytic (digestive) enzymes
-Digest various organelles and nuclear components of the cell- autolysis
-Breakdown of nutrient molecules and intracellular debris
Autolysis
Process of self digestion
Proteasome
Assists with the breakdown and removal of misfolded and damaged unwanted proteins
Peroxisome
-Not produced by Golgi, reproduce by pinching in half
-Common in liver and kidney cells-detoxification
-Contain enzymes (peroxidases and catalsases)
Vaults
-Transportation pods
-Can open and close for pick up and drop off around the cell
Centrioles
-Hollow cylinders made of microtubules
-Found in pairs
-Help to organize the spindle fibers during mitosis
-Form base for cilia and flagella and are called basal bodies
Inclusions
Units of metabolic products that the cell has engulfed
Examples:// Vacuoles, vesicles, lipid droplets, pigment granules, glycogen granules
Vacuoles
Type of inclusion
Clear space in a cell surrounded by cell membrane
“a small emptiness”
Vesicles
Type of inclusion
Small sac containing fluid; membrane bound
Nucleus
-Contains hereditary information
-Controls cell activities through protein synthesis
-Contains all the instructions and information to make over 2000 proteins
-Multinucleated or Anucleated
Nuclear membrane (envelope)
-Composed of two lipid bilayers
-The outer layer is continuous with the endoplasmic reticulum
-1/10th of the membrane surface consists of nuclear pores
-Protein molecules can move into the nucleus and RNA can move out
Nucleoplasm
Gel-like substance that fills the nucleus and is similar to cytosol
Chromatin
-Loose, uncondensed form of DNA in the nucleus
-Composed of DNA wound around globular proteins called histones
-Arranged in loose fibers in the nucleoplasm when the cell is not dividing
-Condenses into super coiled, X-shaped structures called chromosomes during division
-Pairs of identical chromatids are linked together centrally at the centromere to form each chromosome
Nucleoli
-A cell may contain one or more
-No membrane
-Ribosomal subunits are manufactured here
-Contains DNA that codes for rRNA
Diffusion
Moving down a concentration gradientF
Facilitated diffusion
Passive membrane process
-Requires a carrier protein
-Larger molecules and non lipid soluble molecules
-Example:// glucose
-Rate limited by number of available carrier proteins
Osmosis
Passive membrane process
-Movement of water through a semipermeable membrane into a solution where the water concentration is lower (opposite direction of diffusion)
Osmotic pressure
the force of water moving from one side of the membrane to the other
Oncotic pressure
the difference between the osmotic pressure of blood and that of interstitial fluid
Isotonic
-ECF and ICF have the same concentration of dissolved substances
What happens to cell if the extracellular fluid is hypotonic?
Swell will swell and eventually burst
What happens to cell if the extracellular fluid is hypertonic?
Cell will shrink
Filtration
Passive membrane process
-Hydrostatic pressure (bp) pushes liquids through a membrane
-Based on a pressure gradient rather than a concentration gradient
-Occurs in the kidney where blood is filtered through special capillaries to make urine
Active transport
Active membrane process
-Requires a carrier protein
-All cells actively transport Na+, K+, Ca2+, and Mg2+
-Usually against the concentratino gradient
Na+/K+ antiport
Active membrane process
-K+ higher inside the cell and Na+ higher outside the cell
-K+ diffuses out of the cell and Na+ diffuses into the cell
-Cell must actively pump K+ into the cell and Na+ out of the cell: 2K+ ions move in and 3 Na+ ions move out
-This maintains membrane potential which is crucial to functioning of the cell
Endocytosis
Active membrane process
-Cell membrane involutes, engulfs a substance, and closes the cell membrane around it, forming a vesicle
-Phagocytosis and pinocytosis
-Example:// Macrophages
Phagocytosis
Endocytosis in which a solid substance is engulfed
*Process of eating by cells
Pinocytosis
Endocytosis in which a liquid substance is engulfed
*Process of drinking by cells
Macrophage
A type of wbc that phagocytizes debris, dead cells, and invaders
Exocytosis
Active membrane process
-Substances packaged in vesicles by the ER and Golgi body move through the cytoplasm, fuse with the cell membrane and release contents into the ECF
-Excretion or secretion
*Processing out of a cell
Intracellular
within cells
Extracellular
outside of cells
Inorganic chemistry
Structure, synthesis, and bonding of any material in which metals and metalloid elements are of primary interest
Intercellular
between cells
Organic chemistry
Study of compounds containing carbon; ALL living things contain carbon
Biochemistry
Study of living systems from a chemical viewpoint
Covalent bonding
Electron sharing!
-Electrons from one atom are attracted to another atom and vice versa
-The electron shells will eventually overlap and the electrons are shared
Ionic bonding
Electron transfer!
-One atom transfers an electron to another atom
-Basis of this bond is the attraction between the cation and the anion
Hydrogen bonding
Electrostatic attraction!
-A hydrogen atom is bonded to a small, highly electronegative element
-Polarity of molecules is a facter
-H2O molecules
Organic compounds
Contain hydrocarbon groups
-Carbohydrates
-Lipids
-Proteins
-Nucleic acids
Inorganic compounds
Do not contain hydrocarbon groups
-water
-salts
-acids
-bases
Cranial
pertaining to the head
Caudal
pertaining to the tail
Dorsal
pertaining to the back
Ventral
pertaining to the belly
Lateral
pertaining to the side
Medial
pertaining to the middle
Palmar
pertaining to the sole of the forefeet
Plantar
pertaining to the sole of the hindfeet
Mitosis
a single cell divides into two identical daughter cells with identical genetic material of the original cell each with the potential to divide again and pass on an identical copy of its DNA
Stages of Mitosis
Prophase, metaphase, anaphase, telophase
Prophase
-Chromatin condenses into chromosomes
-Cytoskeleton disassembled
-Centrioles begin to migrate to the poles and the mitotic spindle is formed
-Nuclear membrane disintegrates
Metaphase
-Chromosomes line up in the middle of the cell along the mitotic spindle
-The centromere of each chromosome is attached to a single spindle fiber
Anaphase
-Centromeres split
-Each chromatid becomes its own chromosome and the twin chromosomes are pulled away from each other and toward the centrioles
-Errors here are devastating
Telophase
-Chromosomes reach poles and begin to return to chromatin form
-Nuclear membrane forms, nucleoli appears
-Spindle microtubules disassemble
-Cell cleavage
Cytokinesis
The conclusion of mitosis in which the cytoplasm divides
Replication
synthesis of an exact copy of a cell’s DNA to be passed along to the daughter cell when the cell divides
Membrane potential
defined as voltage or electrical potential caused by the separation of oppositely charged particles
Resting membrane potential
The charge difference between the inside and outside of a cell
Flagella
Found singly and are longer; responsible for motility of some cells
Cilia
occur in large numbers and are shorter; move synchronously and propel fluids across the cell surface
Glycocalyx
the sugar coating that covers the surface of some cells
-Provides cell-to-cell adhesion
-acts as a biological marker for recognition between cells and antibodies and cells and viruses
Protein synthesis
-Instructions are contained in the DNA in the nucleus of the cell
Gene
a subunit of the DNA molecule that contains all the information needed to make one peptide chain
Genetic code
the sequence of nitrogenous base pairs that code for amino acids; the genetic code is said to be redundant, meaning that more than one codon codes for the same amino acid
Codon
genetic code of a single amino acid expressed as three bases
Promotors
Codons that signal start here
Terminators
Codons that signal stop here
Translation
the process of manufacturing a new protein using the information on the mRNA molecule
Transcription
the formation of mRNA in the nucleus
Causes of mutation
-spontaneous
-viruses
-ionizing radiation
-chemicals
-fetal mutagens- chemotherapeutic agents, inhaled anesthetics
Enzymes
-proteins that speed up chemical reactions in the body
-Enzymes react with specific substrate to produce a product
Metabolism
-a multi-enzymatic process
-a product formed by one reaction becomes the substrate for the next
-some metabolic pathways will use up to 2- enzyme driven steps
Activation energy
energy used to start the chemical reaction
Anemia
a condition in where there is decreased oxygen carrying capacity of the blood
Atom
smallest unit of an element that retains the unique properties of that element
Atomic weight
Sum of the atomic mass of the protons and neutrons
Atomic number
number of protons in that atom
Ions
positive or negatively charged atoms
Isotopes
atoms that contain a different number of neutrons than normal
Electron shell
area around the nucleus where the electrons are most likely to be found
Molecule
smallest particle of a substance composed of two or more atoms that retains the properties of the substance
Compound
A substance made up of two or more elements
Carbohydrates
-Provide energy
-Store energy
-Building of cellular structures
-Composed of carbon, hydrogen, and oxygen
Examples: table starch, starch, and cellulose
Lipids
-Composed of carbon, hydrogen, and oxygen
-Used in the body for energy
-Stored in fat tissue for future use
-Chemical messengers: hormones
- Classes: neutral fats, phospholipids, steroids, eicosanoids
Saturated fatty acids
all bonds in the hydrocarbon chain are single bonds
-found in animal fats (butter, lard)
Unsaturated fatty acid
Some double bonds between carbon and hydrogen atoms
-plant origin (corn, olive oil)
Proteins
-most common type of organic compound found in the body
-functions:
Cell structures
Structure of body tissues
Control chemical reactions
Regulate growth
Defend against invaders
Transport of ions/molecules
-Composed of carbon, hydrogen, oxygen, and nitrogen
-Amino acids are the building blocks
-Shape determines function
Nucleic acids
DNA and RNA
ATP
adenosine triphosphate
-stores energy in the cell
-created through cellular respiration
Tissues
-cells of similar type and function that are clustered into layers, sheets, or groups
-the cells composing a tissue or differentiated and have lost the ability to survive independently
Tight junctions
-Fusion of outer membranes of adjoining cells
-No matrix filled space between the cells at the site of fusion
Desmosomes
-A strong, welded plaque that connects plasma membranes of adjacent cells
-Filaments interlock with one another and also extend into the cytoplasm as anchors
Gap Junctions
-Connexons extend from the cytoplasm of one cell to the cytoplasm of the other
-Allow the exchange and passage of nucleotides, AAs, sugar, ions and other nutrients
Simple squamous epithelia
-Protected areas of the body
-Often involved in the passage of gas or liquid
-Important in reducing friction of the body
Simple cuboidal epithelia
-Single layer of cubical cells
-Protected regions of body
-Involved in secretion and absorption