Angiogenesis Flashcards
1
Q
Differences between arteries and veins
-location of the majority of blood
A
Thicker TM in artery
Wider lumen in vein
65% in veins
30% in arteries
5% in capillaries
2
Q
Neovascularisation periods
- normal
- pathological
A
Ovulation, menstruation, placenta formation
Wound healing
Retinal development - retinopathies
Tumours
RA, PsA
3
Q
Definitions of -vasculogenesis -angiogenesis -arteriogenesis When do these processes mainly happen
A
Vasculogenesis - new vessels from progenitors
- in embryogenesis
- mesoderm forms => blood islands form and fuse and differentiate, forming new vessels
Angiogenesis - new capillaries from existing ones
- hypoxia
- cells migrate towards VEGF and develop
Arteriogenesis - new arteries from existing ones
-fluid shear stress