Angina pectoris

Question 1

nitrogycerin

Answer 1

both classic and variant angina
sublingually and transdermally

dilates veins and coronary arteries

combo w/ beta blocker

Question 2

isosorbide di/mono- nitrate

Answer 2

both classic and variant angina
oral admin

dilates veins and coronary arteries

combo w/ beta blocker

Question 3

amlodipine

Answer 3

CCB - non-cardioactive
arterial dilation –> increase O2 supply
stable classic angina and variant angina

combo w/ beta blocker

Question 4

extended release nifedipine

Answer 4

CCB - non-cardioactive
arterial dilation –> increase O2 supply
stable classic angina and variant angina

combo w/ beta blocker

Question 5

verapamil

Answer 5

CCB - cardioactive
arterial dilation –> increase O2 supply
Cardiac suppresion –> decrease O2 demand

**1st choice for variant angina pectoris

Question 6

propranolol

Answer 6

beta blocker - non-selective
only for classic angina
decrease O2 demand

combo w/ organic nitrates

Question 7

atenolol

Answer 7

beta blocker - cardioselective
only for classic angina
decrease O2 demand

combo w/ organic nitrates

Question 8

aspirin

Answer 8

anti-platelet
75-81 mg = protection against acute MI
moderate to high risk individuals

Question 9

clopidogrel

Answer 9

anti-platelet - ADP blocker

high risk individuals

Question 10

prasugrel

Answer 10

anti-platelet - ADP blocker

high risk individuals

Question 11

urokinase

Answer 11

fibrinolytic/ clot buster

after acute MI (best within 5-6 hrs)