Anemia Drugs

Question 1

Iron Supplements

Answer 1

PK: PO or parenteral (if unable to tolerate PO)
leading cause of poisoning fatalities in young children

Question 2

Vitamin B12 Supplements

Answer 2

PK: PO preferred or IV if neurological s/s are present
Adverse Effects: hypokalemia (due to increased erythrocyte production)

Question 3

Folic Acid Supplements

Answer 3

PK: PO preferred
Prophylactic use is recommended during pregnancy and breastfeeding

Question 4

Epoetin alfa, darbepoetin alfa

Answer 4

Exogenous EPO
PK: subQ/IV only
Indications: anemia due to kidney disease, chemo-induced anemia, anemia pre-operatively
Adverse Effects: HTN, CV events

Question 5

Filgrastim

Answer 5

Exogenous Leukopoietic GF
PK: subQ/IV only
Indications: treat or avoid low WBC
Adverse Effects: leukocytosis, bone pain

Question 6

Exogenous Thrombopoietin

Answer 6

Indications: idiopathic thrombocytopenia purpura, thrombocytopenia with liver disease pre-operatively