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N544 > Endocrine Drugs > Flashcards

Endocrine Drugs Flashcards

1
Q

Lispro

A

rapid acting insulin

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2
Q

Aspart

A

rapid acting insulin

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3
Q

Glulisine

A

rapid acting insulin

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4
Q

Regular insulin

A

short acting rapid insulin
IDENTICAL TO ENDOGENOUS INSULIN

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5
Q

NPH

A

intermediate acting insulin

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6
Q

U-100 glargine

A

long acting insulin

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7
Q

Demetir

A

long acting insulin

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8
Q

U-300 glargine

A

ultra-long acting insulin

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9
Q

Degludec

A

ultra-long acting insulin

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10
Q

Metformin

A

Biguanide (oral antidiabetic)
CONTRAINDICATED IN HYPOPERFUSION STATES

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11
Q

Glipizide

A

Sulfonylurea (oral antidiabetic)
RISK FOR HYPOGLYCEMIA

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12
Q

Glyburide

A

Sulfonylurea (oral antidiabetic)
RISK FOR HYPOGLYCEMIA

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13
Q

Nateglinide

A

Meglitinide (oral antidiabetic)
RISK FOR HYPOGLYCEMIA
ONLY TAKE WITH MEAL

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14
Q

Repaglinide

A

Meglitinide (oral antidiabetic)
RISK FOR HYPOGLYCEMIA
ONLY TAKE WITH MEAL

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15
Q

Pioglitazone

A

Thiazolidinediones (oral antidiabetic)
INSULIN MUST BE PRESENT

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16
Q

Rosiglitazone

A

Thiazolidinediones (oral antidiabetic)
INSULIN MUST BE PRESENT

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17
Q

Acarbose

A

Alpha-glucose inhibitor (oral antidiabetic)

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18
Q

Miglitol

A

Alpha-glucose inhibitor (oral antidiabetic)

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19
Q

Dipetidyl peptidase-4 (DDP-4) inhibitors

A

oral antidiabetic
prevents glucose from rising too high AFTER MEALS

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20
Q

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors

A

oral antidiabetic
increases renal excretion of glucose

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21
Q

Myline mimetic

A

oral antidiabetic
Prevents postprandial rise

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22
Q

Glucagon

A

Glucagon like peptide (GLP-1) receptor agonist

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23
Q

Somatostatin analogs

A

GH inhibitor

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24
Q

GH receptor antagonists

A

GH inhibitor

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25
Q

Somatropin

A

GH replacement
GIVEN IM or SUBQ

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26
Q

Cabergoline

A

Dopamine agonist for hyperprolactinemia

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27
Q

Bromocriptine

A

Dopamine agonist for hyperprolactinemia

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28
Q

Vasopressin

A

ADH replacement
CAUSES VASOCONSTRICTION
Educate patient on decreasing water consumption

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29
Q

Desmopressin (DDAVP)

A

ADH replacement
Educate patient on decreasing water consumption

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30
Q

Hydrocortisone

A

Glucocorticoid replacement
IDENTICAL TO CORTISOL
Both glucocorticoid and mineralocorticoid actions

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31
Q

Dexamethasone

A

Glucocorticoid replacement
Primarily glucocorticoid actions

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32
Q

Prednisone

A

Glucocorticoid replacement

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33
Q

Spironolactone

A

K+ sparing diuretic
Tx of mineralocorticoid EXCESS

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34
Q

Fludrocortisone

A

Tx of mineralocorticoid DEFICIENCY

35
Q

Levothyroxine

A

Synthetic T4 for hypothyroidism
MUST BE GIVEN ON EMPTY STOMACH
Takes 1 month to plateau
Note: lots of drug interactions

36
Q

Liiothyronine

A

Synthetic T3 for hypothyroidism
Used for myxedema coma (bc quick acting) or if a patient cannot convert T4 to T3

37
Q

Methimazole

A

Thionamide
Preferred because longer 1/2 life, more potent, less adverse effects
Can take 3-12 weeks for full effects

38
Q

Propylithiouracil (PTU)

A

Thionamide for hyperthyroidism
Preferred in 1st trimester pregnancy bc of less placental crossing
Preferred in thyroid storm

39
Q

Lugol solution

A

Nonradioactive iodine
Inhibits T3/T4 synthesis and release

40
Q

Tamoxifen

A

Selective Estrogen Receptor Modulators (SERMs)
Risk for endometrial CA

41
Q

Raloxifene

A

SERMs
No risk for endometrial CA

42
Q

Bazedoxifene

A

SERMs
Good for vasomotor symptoms
No risk for endometrial CA

43
Q

Combination oral contraceptives

A

Estrogen + Progestin

44
Q

Minipills

A

Progestin only
Taken everyday
Good for those at risk for thromboembolism, etc.

45
Q

Transdermal patch

A

Nonoral contraceptive

46
Q

Vaginal ring

A

Nonoral contraceptive

47
Q

Subdermal etonogestrel implant

A

Progestin only
Long acting contraceptive
3-5 years

48
Q

Depot medroxyprogesterone acetate

A

Long acting contraceptive
Black box warning for bone loss
3+ months
Don’t use more than 2 years

49
Q

Copper IUD

A

Long acting contraceptive
10+ years

50
Q

Levonorgestrel IUD

A

Long acting contraceptive
5-7 years

51
Q

Mifepristone + Misoprostol

A

Medical abortion
Misoprostol = prostaglandins to ripen cervix
Mifepristone = progesterone to expel conceptus

52
Q

Clomiphene

A

Drug for follicular maturation
Provides negative feedback (blocking estrogen receptors to increase FSH)

53
Q

Menotropin

A

Drug for follicular maturation
50:50 combo of LH/FSH

54
Q

Follitropins

A

Drug for follicular maturation
FSH

55
Q

hCG + choriogonadotropin alfa

A

Drugs for ovulation
Note: hCG may result in false + pregnancy

56
Q

Cabergoline

A

Dopamine agonist for hyperprolactinemia

57
Q

Bromocriptine

A

Dopamine agonist for hyperprolactinemia

58
Q

Terbutaline

A

b2 agonist for tocolytics

59
Q

Nifedipine

A

Calcium channel blocker for tocolytics

60
Q

Indomethacin

A

COX inhibitor for tocolytics
Inhibits PGs

61
Q

Magnesium sulfate

A

Neuroprotection for fetus during tocolytics
Affects ACh at the NMJ

62
Q

Hydroxyprogesterase caproate

A

Drug for prevention of preterm labor

63
Q

Dinoprostone

A

Prostaglandin for cervical ripening

64
Q

Misoprostol (Cytotec)

A

Prostaglandin for uterine contraction during medical abortion
Also used for PP hemorrhage

65
Q

Oxytocin (Pitocin)

A

Stimulates uterine contractions
Also used for PP hemorrhage

66
Q

Caboprost tromethamine (Hemabate)

A

Used for PP hemorrhage

67
Q

Methylergonovine (Methergine)

A

Used for PP hemorrhage
ONLY IN EMERGENCIES
Contraindicated for HTN

68
Q

Tranexamic acid (TXA)

A

Drug for menorrhagia
Contraindicated for thromboembolism bc causes decrease fibrin mesh breakdown

69
Q

Testosterone enanthate

A

Testosterone & testosterone esters

70
Q

Testosterone cypionate

A

Testosterone & testosterone esters

71
Q

Methyltestosterone

A

17-alpha-alkylated compounds
Only one that can be given PO
Can cause hepatotoxicity

72
Q

Sildenafil

A

Phosphodiesterase inhibitor for ED

73
Q

Vardenafil

A

Phosphodiesterase inhibitor for ED

74
Q

Tadalafil

A

Phosphodiesterase inhibitor for ED
Long acting

75
Q

Avanafil

A

Phosphodiesterase inhibitor for ED
Fastest onset

76
Q

Alprostadil

A

Drug for ED
Injected

77
Q

Papaverine + phentolamine

A

Drug for ED
Injected

78
Q

SSRIs and topical anesthetics

A

Drugs used for premature ejaculation

79
Q

Finateride

A

5-alpha reductase inhibitor for BPH
Promotes regression of epithelial tissue

80
Q

Dutasteride

A

5-alpha reductase inhibitor for BPH
Promotes regression of epithelial tissue

81
Q

Silodosin

A

A1 selective antagonist for BPH
Relaxes smooth muscle and decrease dynamic obstruction

82
Q

Tamsulosin

A

A1 selective antagonist for BPH
Relaxes smooth muscle and decreases dynamic obstruction

83
Q

Doxazosin

A

Nonselective alpha antagonist for BPH

84
Q

Terazosin

A

Nonselective alpha antagonist for BPH

N544 (8 decks)

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