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N544 > Endocrine Drugs > Flashcards

Endocrine Drugs Flashcards

1
Q

Lispro

A

rapid acting insulin

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2
Q

Aspart

A

rapid acting insulin

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3
Q

Glulisine

A

rapid acting insulin

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4
Q

Regular insulin

A

short acting rapid insulin
IDENTICAL TO ENDOGENOUS INSULIN

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5
Q

NPH

A

intermediate acting insulin

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6
Q

U-100 glargine

A

long acting insulin

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7
Q

Demetir

A

long acting insulin

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8
Q

U-300 glargine

A

ultra-long acting insulin

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9
Q

Degludec

A

ultra-long acting insulin

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10
Q

Metformin

A

Biguanide (oral antidiabetic)
CONTRAINDICATED IN HYPOPERFUSION STATES

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11
Q

Glipizide

A

Sulfonylurea (oral antidiabetic)
RISK FOR HYPOGLYCEMIA

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12
Q

Glyburide

A

Sulfonylurea (oral antidiabetic)
RISK FOR HYPOGLYCEMIA

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13
Q

Nateglinide

A

Meglitinide (oral antidiabetic)
RISK FOR HYPOGLYCEMIA
ONLY TAKE WITH MEAL

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14
Q

Repaglinide

A

Meglitinide (oral antidiabetic)
RISK FOR HYPOGLYCEMIA
ONLY TAKE WITH MEAL

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15
Q

Pioglitazone

A

Thiazolidinediones (oral antidiabetic)
INSULIN MUST BE PRESENT

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16
Q

Rosiglitazone

A

Thiazolidinediones (oral antidiabetic)
INSULIN MUST BE PRESENT

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17
Q

Acarbose

A

Alpha-glucose inhibitor (oral antidiabetic)

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18
Q

Miglitol

A

Alpha-glucose inhibitor (oral antidiabetic)

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19
Q

Dipetidyl peptidase-4 (DDP-4) inhibitors

A

oral antidiabetic
prevents glucose from rising too high AFTER MEALS

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20
Q

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors

A

oral antidiabetic
increases renal excretion of glucose

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21
Q

Myline mimetic

A

oral antidiabetic
Prevents postprandial rise

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22
Q

Glucagon

A

Glucagon like peptide (GLP-1) receptor agonist

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23
Q

Somatostatin analogs

A

GH inhibitor

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24
Q

GH receptor antagonists

A

GH inhibitor

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25
Somatropin
GH replacement GIVEN IM or SUBQ
26
Cabergoline
Dopamine agonist for hyperprolactinemia
27
Bromocriptine
Dopamine agonist for hyperprolactinemia
28
Vasopressin
ADH replacement CAUSES VASOCONSTRICTION Educate patient on decreasing water consumption
29
Desmopressin (DDAVP)
ADH replacement Educate patient on decreasing water consumption
30
Hydrocortisone
Glucocorticoid replacement IDENTICAL TO CORTISOL Both glucocorticoid and mineralocorticoid actions
31
Dexamethasone
Glucocorticoid replacement Primarily glucocorticoid actions
32
Prednisone
Glucocorticoid replacement
33
Spironolactone
K+ sparing diuretic Tx of mineralocorticoid EXCESS
34
Fludrocortisone
Tx of mineralocorticoid DEFICIENCY
35
Levothyroxine
Synthetic T4 for hypothyroidism MUST BE GIVEN ON EMPTY STOMACH Takes 1 month to plateau Note: lots of drug interactions
36
Liiothyronine
Synthetic T3 for hypothyroidism Used for myxedema coma (bc quick acting) or if a patient cannot convert T4 to T3
37
Methimazole
Thionamide Preferred because longer 1/2 life, more potent, less adverse effects Can take 3-12 weeks for full effects
38
Propylithiouracil (PTU)
Thionamide for hyperthyroidism Preferred in 1st trimester pregnancy bc of less placental crossing Preferred in thyroid storm
39
Lugol solution
Nonradioactive iodine Inhibits T3/T4 synthesis and release
40
Tamoxifen
Selective Estrogen Receptor Modulators (SERMs) Risk for endometrial CA
41
Raloxifene
SERMs No risk for endometrial CA
42
Bazedoxifene
SERMs Good for vasomotor symptoms No risk for endometrial CA
43
Combination oral contraceptives
Estrogen + Progestin
44
Minipills
Progestin only Taken everyday Good for those at risk for thromboembolism, etc.
45
Transdermal patch
Nonoral contraceptive
46
Vaginal ring
Nonoral contraceptive
47
Subdermal etonogestrel implant
Progestin only Long acting contraceptive 3-5 years
48
Depot medroxyprogesterone acetate
Long acting contraceptive Black box warning for bone loss 3+ months Don't use more than 2 years
49
Copper IUD
Long acting contraceptive 10+ years
50
Levonorgestrel IUD
Long acting contraceptive 5-7 years
51
Mifepristone + Misoprostol
Medical abortion Misoprostol = prostaglandins to ripen cervix Mifepristone = progesterone to expel conceptus
52
Clomiphene
Drug for follicular maturation Provides negative feedback (blocking estrogen receptors to increase FSH)
53
Menotropin
Drug for follicular maturation 50:50 combo of LH/FSH
54
Follitropins
Drug for follicular maturation FSH
55
hCG + choriogonadotropin alfa
Drugs for ovulation Note: hCG may result in false + pregnancy
56
Cabergoline
Dopamine agonist for hyperprolactinemia
57
Bromocriptine
Dopamine agonist for hyperprolactinemia
58
Terbutaline
b2 agonist for tocolytics
59
Nifedipine
Calcium channel blocker for tocolytics
60
Indomethacin
COX inhibitor for tocolytics Inhibits PGs
61
Magnesium sulfate
Neuroprotection for fetus during tocolytics Affects ACh at the NMJ
62
Hydroxyprogesterase caproate
Drug for prevention of preterm labor
63
Dinoprostone
Prostaglandin for cervical ripening
64
Misoprostol (Cytotec)
Prostaglandin for uterine contraction during medical abortion Also used for PP hemorrhage
65
Oxytocin (Pitocin)
Stimulates uterine contractions Also used for PP hemorrhage
66
Caboprost tromethamine (Hemabate)
Used for PP hemorrhage
67
Methylergonovine (Methergine)
Used for PP hemorrhage ONLY IN EMERGENCIES Contraindicated for HTN
68
Tranexamic acid (TXA)
Drug for menorrhagia Contraindicated for thromboembolism bc causes decrease fibrin mesh breakdown
69
Testosterone enanthate
Testosterone & testosterone esters
70
Testosterone cypionate
Testosterone & testosterone esters
71
Methyltestosterone
17-alpha-alkylated compounds Only one that can be given PO Can cause hepatotoxicity
72
Sildenafil
Phosphodiesterase inhibitor for ED
73
Vardenafil
Phosphodiesterase inhibitor for ED
74
Tadalafil
Phosphodiesterase inhibitor for ED Long acting
75
Avanafil
Phosphodiesterase inhibitor for ED Fastest onset
76
Alprostadil
Drug for ED Injected
77
Papaverine + phentolamine
Drug for ED Injected
78
SSRIs and topical anesthetics
Drugs used for premature ejaculation
79
Finateride
5-alpha reductase inhibitor for BPH Promotes regression of epithelial tissue
80
Dutasteride
5-alpha reductase inhibitor for BPH Promotes regression of epithelial tissue
81
Silodosin
A1 selective antagonist for BPH Relaxes smooth muscle and decrease dynamic obstruction
82
Tamsulosin
A1 selective antagonist for BPH Relaxes smooth muscle and decreases dynamic obstruction
83
Doxazosin
Nonselective alpha antagonist for BPH
84
Terazosin
Nonselective alpha antagonist for BPH

N544 (8 decks)

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