anatomy final Flashcards
what is the purpose of the thorax?
covers and protects major cardiopulmonary organs
angle of louis
the sternal angle
level of bifurcation of trachea into right and left main stem bronchi
how many true and false ribs?
1-7 are true
8-12 are false
11-12 are floating
where do you place a chest tube?
above the ribs to avoid trauma
what is the function of the lungs?
exchanges gases between air and blood
what is the homeostatic role of the lungs
regulates blood pH
regulates oxygen and carbon dioxide levels
what is external respiration?
exchange of gases in lungs
what is internal respiration?
exchange of gases within cells of the body
all cells require oxygen for metabolism and a means to remove carbon dioxide
conducting zone of the respiratory system
trachea
bronchi
bronchioles
respiratory zone of the respiratory system
respiratory bronchioles
alveolar ducts
alveolar sacs
what nerve innervates the lung?
phrenic nerve and vagus nerve
structures of the upper respiratory system
nose
mouth
pharynx
epiglottis
larynx
trachea
structures of the lower respiratory system
bronchial tree
lungs
sections of the pharynx
nasopharynx - posterior to nose
oropharynx - posterior to mouth
laryngopharynx - superior to larynx
what epiglottis?
lid or flap that covers that larynx and trachea so food does not enter the lungs
describe the trachea
windpipe
mucous membrane lining with cilia
c shaped cartilage rings
what do the bronchi terminate into
air sacs called alveoli
what are alveoli?
resembles a small balloon
CO2 diffuses from the blood and is exhaled
O2 diffuses form alveoli on inspiration
what is the parietal pleura?
outer most layer
inner surface of thoracic cavity and diaphragm
what is the visceral pleura?
inner layer
outer surface of the lung
intrapleural pressure
between 2 membranes
less than atmospheric pressure
how many lobes does the right lung have?
3
how many lobes does the left lung have?
2
where is the cardiac notch
only in the left lung
how many lobe segments does each lobe have?
upper - 3
middle/lingula - 2
lower - 5
functions of lung
humidifies air so that membranes don’t dry out
warms air to maintain body temperature
filters air - cilia move mucus toward oral cavity to be expelled
how many alveoli in the lungs
300 million - provide tremendous surface area
define compliance
ability of lungs to expand
inspiration
disease - emphy, asthma, pneumonia
define elasticity
ability to recoil
expiration
surface tension
force between water molecules can cause the collapse of lungs
decreases compliance
surfactant
type II cells
breaks surface tension within alveoli
premature babies and surfactant
synthesis of surfactant starts in 24-28th week of gestation
need injections of surfactant if premature - essential to breathe
what happens if there is less surfactant
more surface tension - more risk of collapse
cannot breathe without surfactant
restrictive lung disease
less compliance
greater stiffness
cannot inhale
air cannot enter
pulmonary fibrosis
obstructive
loss of recoil
cannot exhale
air cannot leave
emphy, COPD
increase in volume of intrathoracic cavity
increases lung volume
decreases intrapulmonic pressure
causes air to rush into lungs
inspiration
decrease in volume of intrathoracic cavity
decreases lung volume
increases intrapulmonic pressure
causes air to rush out of lungs
expiration
diaphragm
flattens as it contracts
causes pressure changes that cause inspiration
contraction moves abdo contents forward and down
muscles that elevate the ribs
external intercostals
scalenes
sternocleidomastoid
pectoralis minor
pulls ribs laterally and upward
muscles that pull the ribs downwards in forced expiration
internal intercostals
rectus abdominis
internal oblique muscles of abdominal wall
is expiration passive or active?
passive recoil of diaphragm decreases intrathoracic cavity volume
no muscular effort needed at rest
airflow resistance equation
airflow = P1 - P2 / resistance
larger resistance = less airflow
what is the biggest factor affecting airflow at rest?
diameter of airway
what does bronchodilation do in exercise?
decreases resistance to airflow
what is pulmonary ventilation (VE)
amount of air moved in and out of lungs in a given time period
anatomical dead space + alveolar ventilation
VE = TV x f
5000ml = 500ml x 10
tidal volume (TV)
amount of air moved per breath
600ml in men
it is greater in trained athletes
residual lung volume (RLV)
air left in lungs after max exhalation
1200 ml in men
inspiratory reserve volume (IRV)
maximum inspiration at end of tidal inspiration
3000ml
expiratory reserve volume (ERV)
maximum expiration at end of tidal epiration
1200ml
total lung capacity (TLC)
volume in lungs after maximal inspiration
6000ml
TLC = IC + TV + ERV + RLV
forced vital capacity (FVC)
maximum volume expired after maximum inspiration
4800ml
FVC = IRV + TV + ERV
inspiratory capacity (IC)
max volume inspired following tidal expiration
3600ml
IC = IRV + TV
functional residual capacity (FRC)
volume in lungs after tidal expiration
2400ml
FRC = ERV + RLV
what happens to lung volumes during pregnancy?
tidal volume increases
expiratory volume decreases
where does fluid leak out when the heart pumps?
the heart squeezes some fluid out of the capillaries
pressure in early arteries
120 mmHg
pressure in right atrium
5 mmHg
what do B and T cells do?
bring cells to infection so that they can fight it.
function of lymphatic system
collect excess protein-containing interstitial fluid and return it to bloodstream
what is lymph?
fluid that carries cells that help fight infection and disease
four functions of lymphatic system
transport clean fluid back to blood
drains excess fluids from tissues
removes debris from cells
transports fats from digestive system
amount of blood lost throughout capillaries
starts at 20 liters
ends at 17 liters
3 liters drained by lymphatic system
describes how blood leaves the capillaries
wall of capillaries have holes in them
blood oozes out
fills space between cells - called lymph
RBC, WBD, proteins are too larger to come out
what happens to blood when it loses its plasma?
gets thicker and thicker
high viscosity will cause blood clots
tissues will get puffed up and cause swelling
describe how lymphatic vessels flow
they are a one way system to the heart
describe the walls and valves of the collecting vessels in lymphatic
walls are thinner
more internal valves
where are capillaries absent from?
bones
teeth
bone marrow
entire nervous system
what drives movement of lymph
hydrostatic pressure drives entry of lymph into lymphatic capillaries
explain endothelial cells that form walls of lymphatic capillaries
not tightly joined
edges loosely overlap forming minivalves
size of lymph node
how many in body
1 to 25 mm
600 in body
what do WBCs do to lymph inside the nodes
breakdown and help with immunity
what cleans the lymph as it flows through the node?
lymphocytes
macrophages
how can nodes indicates infection?
swollen nodes are early indication of infection
what are lacteals
lymph vessels that take up lots of fats and chylomicrons
where does right lymphatic duct drain?
into junction of right internal jugular and right subclavian veins
where does the thoracic duct drain into?
left internal jugular and subclavian veins
what is the largest lymphatic organ
spleen
what does the spleen do?
filters blood
recycle old RBCs
store platelets and WBCs
fight certain bacteria like pneumonia and meningitis
how many lobe in thymus gland?
2
development of thymus gland
max size in puberty
decreased size in maturity
function of thymus
differentiation and maturation of T cells
what do T cells do once they leave the thymus?
provide immunity
how does edema happen?
when flow of lymph is interfered with
lymphedema
swelling in tissues
can be due to tumor pressure, parasites or surgery
describe elephantiasis
blockage by parasitic worms
infection acquired in childhood causing hidden damage to lymph system
manage by:
wrapping infected limbs and daily washing
what is the endocrine system?
all glands of body that secrete hormones directly into the blood stream
DO NOT CONTAIN DUCTS
what is the difference between endocrine and exocrine?
endo - no ducts
exo- has ducts
what stimulates endocrine glands?
nervous system
chemical changes in body
what is a gland
a structure that produces some substance or material
two types - endo and exo
explain lock and key mechanism in endocrine system
hormone is key
specific sit is lock
are all tissues that are exposed to hormones affected?
no. they only affect their target tissues. they bind to specific receptors and are stimulated by that reaction
basic hormone action
cells have receptors and bind only to that specific hormone type
do hormones carry information?
no, but they are only released to stimulate a chemical reaction
describe tropic hormones
secreted by endocrine to stimulate the activity of another endocrine gland
what is the role of the hypothalamus
monitors the body for temperature, pH, ect
signals pituitary gland if something needs corrected or an emergency needs a response
receives sensory info from the thalamus
what is the adenohypophysis?
anterior lobe of pituitary
what is the neurohypophysis?
posterior lobe of pituitary
hypothalamic control of hormone secretion from adeno:
has neurons that produces hormones and release them. they travel directly to anterior pituitary and release them into systemic circulation
location of pituitary gland
sits on hypophyseal fossa
connects to hypothalamus through stalk called the infundibulum
growth hormone (GH)
signals growth of body
prolactin
stimulates breast tissue to produce milk
thyroid stimulating hormone (TSH)
stimulates thyroid gland to secrete hormones that influence metabolism
adrenocorticotropic hormone (ACTH)
stimulates adrenal gland to signal hormones that help deal with stress
melanocyte stimulating hormone (MSH)
stimulates melanocytes to produce more melanin and darken the skin
follicle stimulating hormone (FSH)
testes or ovaries to stimulate maturation of egg/sperm and induce secretion of sex hormones
lutinizing hormone (LH)
during menstrual cycle and signals ovulation
location of neurohyopohysis
part of brain and composed of neurons
what does neurohypophysis do?
stores hormones produced by hypothalamus and release when stimulated
antidiuretic hormone (ADH)
stimulates collecting tubules of kidney to concentrate urine to reduce water loss.
diabetes insipidus
pee alot (polyuria) and fell thirsty (Polydipsia).
not diabetes but have similar S&S
oxytocin
induces contractions of smooth muscle of sexual organs
describe thyroid gland
two lobes
butterfly shape
thyroid hormone
contain iodine
increase metabolic rate
calcitonin
reduces excessive calcium by slowing down osteoclast activity
actively secreted in childhood to increase bone formation
describe parathyroid gland
posterior to thyroid gland
2-4 pairs of glands
parathyroid hormone (PTH)
opposes calcitonin
increases calcium levels in blood by activating osteoclast, stimulating kidney to reabsorb calcium, or activation of vitamin D production for calcium to be absorbed from food
adrenal gland
two glands within one structure