Anatomy Exam 1 Flashcards
Blood moves
gases, nutrients, wastes, and hormones
Blood components
Formed elements: erythrocytes, leukocytes, platelets
Plasma: fluid portion of blood containing mostly water, proteins, and dissolved solutes
- blood is a colloid
Functions of blood
transportation of formed elements and dissolved solutes, protection against pathogens, Regulates body temperature, pH, and fluid balance
Physical characteristics of blood
Blood color depends on oxidation: bright red if oxygenated, dark red if low oxygen
Volume: 5L
Viscosity: 4-5 times thicker than water
Temp: blood is 1c higher
Blood pH: slightly alkaline
Plasma proteins exert
colloid osmotic pressure: prevent loss of fluid from blood as it moves through capillaries
- can be decreased with diseases
Albumins
most abundant plasma protein
- exerts greatest colloid osmotic pressure
- transport protein for some lipids, hormones and ions
Globulins
The second largest group of plasma proteins
small alpha and larger beta
Gamma-globins are apart of bodies defenses
Fibrinogen
contributes to blood clot formations
- serum is a plasma with clotting proteins removed
Regulatory proteins
includes enzymes and hormones
less than 1% plasma proteins
Hematopoiesis
production of formed elements
- occurs in red bone merrow
Hemocytoblasts are
stem cells
Myeloid lines form
erythrocytes, all leukocytes besides lymphocytes and megakaryocytes
Lymphoid line
only forms lymphocytes
Erythrocytes
red blood cells; lack a nucleus and cellular organs
- can stack and line up forming rouleau
- transports oxygen and Co2 between tissues and lungs
Hemoglobin
-red-pigmented protein
Transport o2 and Co2
- each composed of 4 globins; 2 alpha and 2 beta globins; oxygen binds to iron ions so 4 o2 can bind and Co2 binds to globin protein
How EPO regulates erythrocyte production
Decreased blood o2
Kidney releases EPO
EPO stimulates the bone marrow to increase erythrocytes
Lungs oxygenate erythrocytes increases o2 blood levels
Erythrocyte recycling
Erythrocyte form in red bone marrow
circulate for 120 days
then phagocytized by macrophages in liver and spleen. and components of hemoglobin separate
Globin breaks down my amino acids and moves into blood, iron stored in the liver or secreted, Heme moves into large intestine as stercobilin
Rh blood type
determines if blood is positive or negative; antigen D; positive if present
Agglutination
If blood from another type enters blod, agglutinated erythrocytes block small vessels