Anatomy and Imaging Flashcards
Skeletal muscle in the GI tract is found in the (4)
mouth
pharynx
upper oeso
external anal sphincter
4 activities of the GI tract =
motility (mainly SM)
secretion
digestion
absorption
contains epithelial, exocrine and endocrine gland cells
lamina propria
muscularis mucosae
GI mucosa
4 layers of GI tract wall =
mucosa > submucosa > musularis externa > serosa
Regulates the SA and shape of mucosa layer in gut
muscularis mucosae
Lamina propria of gut wall contains:
capillaries
enteric NS
immune cells
made up of connective tissue, blood and lymph vessels, glands and nerve network
submucosa
regulates the absorptive and secretive functions of the submucosa
Meissner’s/submucosal plexus
___ muscle then _____ plexus (regulates mechanical activity of the gut) then ____ muscle
In typical gut wall muscularis externa
circular
Myenteric/Auerbach’s
longitudinal
Connective tissue layer of gut wall that secretes sticky fluid so gut slides over itself
serosa
Contraction of gut circular muscle causes ___
tube to narrow and lengthen
Contraction of gut longitudinal muscle causes ____
tube to shorten and fatten
3 bands of muscularis externa longitudinal muscle in colon
teniae coli
Slow wave electrical activity in the enteric NS is driven by ____
ICC pacemakers
Interstitial cells of Cajal
ICCs lie in :
between muscle layers of muscularis externa
in submucosa
few in SM cells
___ allow depolarisation and contraction in the gut to occur as a functional syncytium
gap junctions => single unit SM
Upstroke of slow wave electrical activity in the gut is caused by ___
voltage activated Ca2+ channels = Ca2+ influx
Downstroke of slow wave electrical activity in the gut is caused by ____
voltage and Ca2+ activated K+ channels = K+ efflux
ICC are regulated by ,+_
enteric+autonomic nerves
hormones
The force of gut contraction is directly proportional to the ___ from ICC
number of APs produced
Determines the max. frequency, direction and velocity of gut contractions
Slow wave electrical activity - driven by ICCs
BER (basic electrical rhythm) is determined by:
slow wave electrical activity
BER in duodenum is greater/less than in ileum = food moves in ___ direction
greater
aboral
BER in proximal colon is greater/less than in the sigmoid colon = food moves in ___ direction
less
oral