Anatomy

Question 1

Life Span of RBC

Answer 1

120 days

Question 2

Poikilocytosis

Answer 2

Varying shapes of RBCs

Question 3

Anisocytosis

Answer 3

Varying sizes of RBCs

Question 4

Erythrocytosis

Answer 4

polycythemia, increased hematocrit

Question 5

Platelet dense granules

Answer 5

ADP, Calcium, ATP, 5-HT, histamine

platelet adhesion and vasocontriction

Question 6

Platelet alpha granules

Answer 6

vWF, fibrinogen, plasminogen, PDGF

platelet derived GF

Question 7

Life Span of Platelets

Answer 7

8-10days

Question 8

Leukocyte WBC differential from highest to lowest

Answer 8

Neutrophils (54-62%)
Lymphocytes (25-33%)
Monocytes (3-7%)
Eosinophils (1-3%)
Basophils (0-0.75%)

Question 9

Multilobed Nucleus, Phagocytic, acute inflammatory response

Answer 9

Neutrophil

Question 10

Defensins

Answer 10

Neutrophil cationic protein

Question 11

Hypersegmented Neutrophil

Answer 11

5 or more lobes, seen in Vitamin B12/folate deficiency

Question 12

Increased Band cells

Answer 12

Immature neutrophils reflecting states of increased myeloid proliferation (bacterial infections, CML)

Question 13

Reticulocyte

Answer 13

immature erythrocytes, marker of erythroid proliferation

Question 14

Differentiates into macrophages, large, kidney-shaped nucleus. Extensive “frosted glass” cytoplasm

Answer 14

Monocyte

Question 15

Monocytes that migrate into tissue

Answer 15

Histocytes

Question 16

Monocyte life in blood

Answer 16

3 days

Question 17

CD14

Answer 17

cell surface marker for macrophage

Question 18

Important component of granuloma formation

Answer 18

Macrophage

Question 19

Bilobate Nucleus

Answer 19

Eosinophil

Question 20

Crystalloid Body

Answer 20

Eosinophil, major basic protein

Question 21

Helps limit reaction following mast cells degranulation

Answer 21

Eosinophils’ histaminase and arylsulfatase

Question 22

Causes of Eosinophilia

Answer 22

Neoplasia, Asthma, Allergic Processes, Connective Tissue Diseases, Parasites

Question 23

Neutralizes SRS-A of anaphylaxis

Answer 23

Arylsulfatase (from eosinophils)

Question 24

Mediates Allergic Rxn, contain heparin (anticoagulant), histamine(vasodilate), and leukotrienes

Answer 24

Basophils

Question 25

Bilobed nucleus that is obscured with granules

Answer 25

Basophils

Question 26

has FcR for IgE to trigger release

Answer 26

Basophils

Question 27

Isolated basophilia

Answer 27

CML

Question 28

Cell involved in type I HS

Answer 28

Mast Cells

Question 29

Cromolyn

Answer 29

prevents mast cell degranulation (used for asthma prophylaxis)

Question 30

IgE cross-links upon Ag binding causing degranulation releasing histamine, heparin and eosinohpil chemotactic factors

Answer 30

Mast Cells

Question 31

Highly phagocytic APC, functinos as a link between innate and adaptive immune system

Answer 31

Dendritic Cell

Question 32

Dendritic cell in the skin

Answer 32

Langerhands cell

Question 33

Round, densely staining nucleus with small amount of pale cytoplasm

Answer 33

Lymphocytes

Question 34

Express CD19, CD20

Answer 34

B-lymphocyte

Question 35

All T-cells express

Answer 35

CD2, CD3, CD7

Question 36

Primary target for HIV

Answer 36

CD4+T helper cells

Question 37

Co-stimulatory signal necessary for T-cell activation

Answer 37

CD28

Question 38

Clock-face chromatin distribution

Answer 38

Plasma Cell

Question 39

Kills virus infected and tumor cells

Answer 39

NK Cells

Question 40

express CD56

Answer 40

NK Cels

Question 41

Who is fucking tired?

Answer 41

ME!