Anatomy Flashcards
What is Rieger syndrome associated with?
Telecanthus
Rieger syndrome can present with various developmental abnormalities.
Dental = few and small teeth
Facial = maxillary hypoplasia, nasal bridge, hypertelorism (eyes set wide apart)
What does the term ‘pental’ refer to?
Few & small teeth
Pental is a term used in dental anomalies.
What is hypertelorism?
Eyes are set far apart
Hypertelorism is characterized by an increased distance between the eyes.
List the layers of the eyelid.
1.Skin
2. Subcutaneous Areolar Layer
3. Orbicularis Layer
4. Submuscular areolar layer
5. Orbital septum
6. Posterior muscular system
7. Tarsal Plate
8. Palpebral conjunctiva
These layers serve different functions and structures within the eyelid.
What is entropion?
Turning inward of the eyelid
Entropion often leads to irritation of the eye due to eyelashes rubbing against the cornea.
What does telecanthus refer to?
Abnormally increased distance between medial canthi
Telecanthus is a condition that can affect the appearance of the eyes.
What is poliosis?
Whitening of the eyelashes
Poliosis can be associated with various conditions, including genetic disorders.
What is madarosis?
Loss of eyelashes
This condition can be caused by various factors, including trauma or disease.
Such as MGD, blepharitis, lid disease, sebaceous gland carcinoma
What is trichiasis?
Turning inward of eyelashes
Trichiasis is often secondary to conditions like entropion.
What is phthiriasis palpebrarum?
Infection of the eyelashes caused by Phthirus pubis
- pubic crab lice
Describe the skin layer of the eyelid.
Thin layer containing fine hairs, sweat glands, and sebaceous glands
This layer is unique as it is the thinnest skin in the body and contains no fat.
What does the subcutaneous areolar layer contain?
Loose connective tissue and levator aponeurosis
The levator aponeurosis is crucial for eyelid elevation.
What is the orbicularis layer?
Contains the palpebral portion of the orbicularis oculi
The orbicularis oculi is a muscle responsible for closing the eyelids.
What is a characteristic of the eyelid skin?
Contains no fat
This anatomical feature contributes to the eyelid’s flexibility and function.
What is the role of the eyelid?
Keeps the eyeball divided into anterior & posterior portions
The eyelid protects the eye and maintains moisture.
Which cranial nerve is responsible for eyelid expression?
CN VII (facial nerve)
CN VII innervates the muscles responsible for facial expressions, including the eyelids.
What happens during paralysis of CN VII?
Causes a brow to be lowered on the affected side and can lead to lagophthalmos
Lagophthalmos refers to the inability to close the eyelids fully.
What are the two portions of the orbicularis oculi?
- Orbital portion
- Palpebral portion
These portions serve different functions in eyelid movement.
What is the function of the orbital portion of the orbicularis oculi?
Used for forced closure of the eyelids
The orbital portion attaches to the orbital margins and extends outward.
What is the function of the palpebral portion of the orbicularis oculi?
Used for spontaneous and reflex blinking
This portion helps in gentle eyelid closure.
What is the muscle of Riolan?
Most superficial portion of the orbicularis oculi that keeps the lid margin tightly applied to the globe
Also known as the pars ciliaris.
What is the gray line?
A groove located between the eyelash insertions and the meibomian glands
It serves as a surgical landmark during lid repair.
What condition results from paralysis of the orbicularis oculi?
Ectropion
Ectropion is characterized by the lower eyelid drooping away from the globe.
What is the muscle of Horner?
Consists of fibers from the orbicularis that help drain tears into the lacrimal sac
Also referred to as the pars lacrimalis.
What is the anatomical origin of the muscle of Horner?
Originates from the posterior lacrimal crest and fascia of the lacrimal sac
It encircles the canaliculi to assist in tear drainage.
What does paralysis of the orbicularis oculi lead to?
Drooping of the lower eyelid and potential eversion of the lid
This can also lead to discomfort and red eye due to improper eyelid function.
Fill in the blank: The gray line divides the lid into _______ and posterior portions.
anterior
This anatomical feature is important for surgical procedures.
What is the submuscular areolar layer?
Thin layer of loose connective tissue between the orbicularis and the orbital septum
Contains the levator aponeurosis and the palpebral portion of the main lacrimal gland
What is the function of the orbital septum?
Serves as a barrier to the orbit in the upper and lower eyelids
Prevents fat from falling onto the lid margins and keeps infections localized to the anterior portion of the eyelid
True or False: The orbital septum protects the lacrimal sac from infection.
False
The lacrimal sac is anterior to the attachment of the orbital septum
What does preseptal cellulitis refer to?
An infection that occurs anterior to the orbital septum
Commonly seen in cases of eyelid infections
What is orbital cellulitis?
An infection that occurs posterior to the orbital septum
More serious than preseptal cellulitis, often involving the orbit itself
What are the components of the posterior muscular system of the eyelid?
Superior levator palpebrae muscle, superior tarsal muscle, inferior tarsal muscle
These muscles control eyelid elevation and positioning
Where does the superior palpebral levator muscle originate?
From the lesser wing of the sphenoid at the orbital apex
It serves as the main retractor of the upper eyelid
What is the role of Whitnall’s ligament?
Serves as a fulcrum for the levator muscle
Changes the course of the muscle, allowing it to perform its function effectively
Fill in the blank: The levator muscle extends into the eyelid as a fan-shaped tendon known as the _______.
levator aponeurosis
This tendon sends fibers anteriorly through the orbital septum
What is the significance of the medial and lateral horns of the levator aponeurosis?
The lateral horn attaches to Whitnall’s ligament; the medial horn merges with the medial palpebral ligament
Important for the structural integrity and function of the eyelid
What is the clinical implication of CN III palsy on the eyelid?
Results in ptosis, or drooping of the upper eyelid
CN III is responsible for innervating the levator palpebrae muscle
What is the function of the levator palpebrae superioris?
Elevates the upper eyelid
What forms the superior palpebral furrow?
Insertion of the levator aponeurosis into the skin of the upper eyelid
What forms the inferior palpebral furrow?
Indirect attachment of the inferior rectus muscle into the skin of the lower eyelid
What separates the tarsal and orbital portions of the eyelid?
Eyelid furrows
What is the role of the Muscle of Muller?
Provides minor retraction of the upper eyelid and widens the palpebral fissure
Which receptors does the Muscle of Muller respond to?
Alpha-1 adrenergic receptors
What is another name for the Muscle of Muller?
Superior tarsal muscle
Where does the inferior tarsal muscle originate?
Fascial sheath of the inferior rectus
What causes mild upper lid ptosis in Horner’s syndrome?
Lack of sympathetic innervation to the Muscle of Muller
What is the result of CN III palsy?
Significant upper lid ptosis
What condition can cause a ‘stare appearance’ in patients?
Thyroid eye disease
What is the normal interpalpebral fissure distance in adults?
10-12 mm
Which cranial nerve opens the eye?
Cranial Nerve III (CN III)
Which cranial nerve closes the eye?
Cranial Nerve VII (CN VII)
______ is the smooth muscle innervated by the sympathetic nervous system that raises the eyelid.
Muscle of Muller
True or False: Cocaine can maintain the eye being open.
True
What is the effect of sympathetic input on pupil dilation?
Will not dilate the pupil in the absence of sympathetic input
List the adrenergic receptors available to bind norepinephrine.
- A1
- A2
- B1
- B2
What is the primary function of the Meibomian glands?
To produce the anterior lipid layer of the tear film
Meibomian glands are large sebaceous glands located within the tarsal plate
How many Meibomian glands are approximately in the upper eyelid?
About 25 Meibomian glands
There are approximately 20 glands in the lower eyelid
What type of tissue composes the tarsal plate?
Dense irregular connective tissue
This tissue provides rigidity to the eyelids
What are the two layers of the palpebral conjunctiva?
- Epithelial layer
- Stroma
The epithelial layer contains goblet cells that produce mucin for the tear film
Where are goblet cells predominantly found?
In the inferonasal fornix and on the bulbar conjunctiva
Most concentrated temporally
What does the stroma of the palpebral conjunctiva contain?
Superficial lymphoid layer and deep fibrous layer
The superficial lymphoid layer is immunologically active
What is the function of the Glands of Zeis?
To lubricate the eyelashes
They are modified sebaceous glands associated with eyelash follicles
True or False: The Glands of Moll are modified sebaceous glands.
False
Glands of Moll are modified apocrine glands located near the lid margin
Fill in the blank: The upper and lower tarsal plates combine to form the _______.
Medial and lateral palpebral ligaments
The medial palpebral ligament attaches to the maxillary bone
What type of immune cells are found in the superficial lymphoid layer of the conjunctiva?
IgA, macrophages, mast cells, PMNs, eosinophils
This layer is very immunologically active
What are the accessory lacrimal glands located in the fornices of the conjunctiva called?
Glands of Krause
They are considered merocrine glands
What is exocytosis?
A process where cells secrete substances by expelling them from vesicles, allowing the cells to remain intact.
What are the Glands of Wolfring?
Accessory lacrimal glands that are larger and less numerous than the glands of Krause, located predominantly in the tarsal conjunctiva.
What type of glands are the Meibomian glands and glands of Zeis?
Holocrine glands.
What type of glands are the Glands of Moll and goblet cells?
Apocrine glands.
What type of glands are the accessory lacrimal glands?
Merocrine glands.
During holocrine secretion, what happens to the cell?
The whole cell is shed into the lumen.
During apocrine secretion, what occurs?
A portion of the plasma membrane buds off the cell and enters the lumen for secretion.
In merocrine secretion, how do cells secrete their substances?
Cells secrete their substances by exocytosis and remain completely intact after secretion.
True or false
There are more glands of Krause than Wolfring
True
* more glands of Krause but wolfing glands are larger
What is the orbicularis oculi?
A muscle of the eyelids with concentric fibers that act as a sphincter to close the eyelids
It consists of palpebral and ciliary portions.
Which nerve innervates the orbicularis oculi?
Zygomatic branch of the facial nerve
It provides voluntary motor innervation.
What type of innervation does the muscle of Muller receive?
Involuntary motor innervation from the sympathetic nervous system
This muscle assists in elevating the upper eyelid.
What branches supply sensory innervation to the upper eyelid?
Frontal (supraorbital and supratrochlear) and lacrimal branches of V1 (ophthalmic nerve)
These branches are responsible for sensory perception in the upper eyelid.
Which branches innervate the lower eyelid?
Infraorbital and zygomaticofacial branches of V2 (maxillary nerve)
These branches provide sensory innervation to the lower eyelid.
What is the role of the infratrochlear nerve?
Innervates the medial aspect of the upper and lower eyelids
It branches from the nasociliary nerve of V1.
What arteries supply the deeper eyelid tissue?
Lateral and medial palpebral arteries, branches of the ophthalmic artery
These arteries are crucial for blood supply to the eyelids.
Where are the palpebral arcades located?
In the submucosal areolar layer of the upper and lower eyelids
They are formed by the union of the medial and lateral palpebral arteries.
What are the two main types of palpebral arcades?
Marginal palpebral arcades and Peripheral palpebral arcades
Marginal palpebral arcades are located closest to the eyelid margin, while Peripheral palpebral arcades supply the fornices and the posterior conjunctiva.
What is the role of the anterior ciliary arteries?
Provide circulation to the bulbar conjunctiva and the ciliary body
This explains why patients with uveitis can experience circumlimbal injection and decreased aqueous humor production in the involved eye.
Which arteries supply the superficial areas of the eyelid?
Facial artery
The facial artery branches off the external carotid artery.
What condition can lead to circumlimbal injection?
Uveitis
Uveitis can cause inflammation leading to circumlimbal injection and decreased aqueous humor production.
Fill in the blank: The _______ supplies circulation to the deeper eyelid structures.
Arcades
True or False: The veins of the eyelids drain into the palpebral and ophthalmic arteries.
False
The veins of the eyelids drain into the palpebral and ophthalmic veins, not arteries.
What is the function of the medial palpebral artery?
Supplies circulation to the medial aspect of the eyelid
It is a branch of the ophthalmic artery.
What is the approximate volume of aqueous humor in the anterior chamber?
200 microliters
List the main branches of the external carotid artery that supply the eyelids.
- Facial artery
- Lacrimal artery