ANATOMICAL PATHOLOGY 2.2(THROMBOEMBOLIC VASCULAR OCCLUSION )

Question 1

THROMBOSIS

Answer 1

SOLIDIFICATION OF BLOOD CONTENTS FORMING WITHIN THE VASCULAR SYSTEM DURING LIFE

Question 2

PRIMARY ABNORMALITIES LEADING TO THROMBOSIS

Answer 2

ENDOTHELIAL INJURY
HYPERCOAGULABILITY
ALTERATION IN BLOOD FLOW

Question 3

ENDOTHELIAL INJURY CAUSES

Answer 3

INFLAMMATION

HYPERCHOLESTEROLEMIA

Question 4

ABNORMAL BLOOD FLOW CAUSES

Answer 4

STASIS:PROLONGED BED REST ATRIAL FIBRILLATION
TURBULANCE:ATHEROSCLERIC VESSEL NARROWING,ANEURYSM

Question 5

HYPERCOAGULABLE STATES

Answer 5

DISORDER OF BLOOD THAT MAY CAUSE THROMBOSIS

PRIMARY:FACTOR V MUTATION,PROTEIN V &S DEFICIENCY
ACQUIRED: PROSTHETIC VALVES MYOCARDIAL INFARCTION PROLONGED BED REST AND MOBILIZATION TISSUE INJURY

Question 6

VENOUS THROMBOSIS

Answer 6

AKA PHLEBOTHROMBOSIS
ALMOST INVARIABLY OCCLUSIVE
THROMBUS TAKE SHAPE OF THE VEIN
THROMBUS FORM IN A RELATIVELY STATIC ENVIROMENT

Question 7

SUPERFICIAL THROMBI

Answer 7

COMMONLY OCCUR IN SAPHEOUS VEIN OF THE LEG IN SETTING OF VARICOSITIES,CAUSE LOCAL PAIN SWELLING AND CONGESTION
RARELY EMBOLISE BUT PREDISPOSE TO ULCERATION OF OVERLYING SKIN

Question 8

DEEP VEIN THROMBI

Answer 8

ASSOCIATED WITH HYPERCOAGULABLE STATES
COMMONLY AFFECTS BIG VEINS AT OR ABOVE THE KNEE
EMBOLISES

Question 9

ARTERIAL AND CARDIAC THROMBOSIS

Answer 9

RHEUMATIC HEART DISEASE MAY CAUSE ATRIAL MURAL THROMBI CAUSING ATRIAL DILATION AND FIBRILLATION

Question 10

MURAL THROMBOSIS CAUSES

Answer 10

MYOCARDIAL INFARCT
ARRHYTHMIAS
DILATED CARDIOMYOPATHY
\CARDIAC ANEURYSMS

Question 11

FATE OF THROMBI

Answer 11

PROPAGATION
EMBOLIZATION
DISSOLUTION
ORGANISATION AND RECANALIZATION