ANATOMICAL PATHOLOGY 2.2(INFECTIVE ENDOCARDITIS) Flashcards
STREPTOCOCCUS VIRIDANS
50-60 % OF CASES A NORMAL CCOMPONENT OF ORAL CAVITY FLORA
ENDOCARDITIS OF NATIVE BUT PREVIOUSLY DAMAGED VALVES/ABNORMAL VALVE
S.AUREUS
HEALTHY OR DEFORMEWD VALVES
INTRAVENOUS DRUG ABUSERS
OTHER BACTERIA
ENTEROCCI AND SO CALLED HACEK GROUP(HAEMOPHILUS ACTINOBACILLUS CARDIOBACTERIUM EIKENELLA KINGELLA)
CLASSIFICATION
ACUTE AND SUBACUTE
ACUTE
CAUSED BY INFECTION OF A PREVIOUSLY NORMAL HEART BY A HIGHLY VIRULENT ORGANISM (STAPHYLOCOCCUS AUREUS)THAT RAPIDLY PRODUCES NICROTISING AND DESTRUCTIVE LESIONS
SUBACUTE
ORGSNISMS WITH A LOW VIRULENCE .E.G. VIRIDANS STREPTOCOCCI CAUSE INSIDIOUS INFECTIONS OF DEFORMED VALVES WITH OVERALL DESTRUCTIONS
RISK FACTORS
RHEUMATIC HEART DISEASE WITH VALVULAR SCARRING MITRAL VALVE PROLAPSE DEGENARATIVE CALCIFIC VALVULAR STENOSIS BICUSPIC AORTIC VALVE PROSTHETIC VALVE CONGENITAL DEFECTS
PROSTHETIC VALVE ENDOCARDITIS
USUALLY CAUSED BYNEGATIVE STAPHYLOCOCCI S.EPIDERMIDIS
PREDISPOSING FACTORS
DIABETES
TOOTH EXTRACTION
PRESSURE SORES
SURGICAL PROCEADURES
ORGANISMS FOUND ON SKIN
S.AUREUS
S.EPIDEMIDIS
CANDIDA
MAJORS
BLOOD CULTURE POSITIVE FOR CHARACTERISTIC ORGANISM OR PERSISTENTLY POSITIVE FOR AN UNUSUAL ORGANISM
ECHOCARDIOGRAPHIC IDENTIFICATION OF VALVE-RELATED OR IMPLANT-RELATED MASS OR ABSCESS OR PARTIAL SEPERATION OF ARTIFICIAL VALVE
NEW VALVULAR REGURGITATION
MINORS
FEVER
PREDISPOSING HEART LESIONS OR IV DRUG USE
VASCULAR LESIONS
IMMUNIOLOGICAL PHENOMENA
MICROBIOLOGIC EVIDENCE
ECHOCARDIOGRAPHIC FINDINGS CONSISTENT BUT WITH NO DIAGONISTIC OF ENDOCARDITIS
COMPLICATIONS
LOCAL AND SYSTEMIC
LOOCAL
VALVE INCOMPETENCE WHICH MAY OCCUR DUE TO RUPTURE OF THE VALVE LEAFLETS OR CORDAE THENDONAE
MYOCARDITIS
THROMBO EMBOLISM
AORTIC ROOT ABSCESSES
SYSTEMIC
FEVER
LOSS OF WEIGHT
MALAISE
SPLENOMEGALY
