ANATOMICAL PATHOLOGY 2.2(CARDIOMYOPHATHY)

Question 1

CARDIOMYOPHATHY

Answer 1

LITERALLY MEANS DISEASE TO THE HEART MUSCLE

HEART DISEASE RESULTING FROM ABNORMALITY IN THE MYOCARDIUM

Question 2

CAUSES OF CARDIOMYOPATHY

Answer 2

PRIMARY(INHERITED OR ACQUIRED),UNKNOWN CAUSE

SECONDARY(DUE TO THE INVOLVEMENT OF MYOCARDIUM AS PART OF SYSTEMIC OR MULTI ORGAN DISORDER

Question 3

SECONDARY CAUSES OF CARDIOMYOPATHY

Answer 3

PERRIPATUM
ALCOHOLISM
IATROGENIC

Question 4

CLASSIFICATION

Answer 4

DILATED
HYPERTROPHY
RESTRICTIVE

Question 5

DILATED

Answer 5

DUE TO LEFT VENTRICLE SYSTOLIC DYSFUNCTION AND INCREASED LV DIAMETER
CAUSES MITRAL REGURGITATION
INCREASED CHAMBER VOLUMES
CAUSES ARE PRIMARY OR SECONDARY
CONGESTIVE CARDIOMYOPATHY

Question 6

CAUSES OF DILATED CARDIOMYOPHATHY

Answer 6

GENETIC
ALCOHOL AND OTHER TOXINS
MYOCARDITIS(VIRAL)
IRON OVERLOAD
SUPRAPHYSIOLOGICAL

Question 7

GENETIC

Answer 7

AUTOSOMAL DOMINANR,AUTOSOMAL RECESSIVE,X LINKED,MITOCHONDRIAL

Question 8

ALCOHOL AND OTHER TOXINS

Answer 8

ETHANOL IS TOXIC TO MYOCARDIUM
ALCOHOL AND ITS METABOLITES ARE TOXIC
CHEMOTHERAPHY CAN CAUSE DILATED CARDIOMYOPATHY

Question 9

IRON OVERLOAD

Answer 9

HAEMOCHROMATOSIS

MULTIPLE TRANSFUSIONS

Question 10

MYOCARDITIS(VIRAL)

Answer 10

PERIPARTUM
PIH
VOLUME OVERLOAD
TACHYCARDIA
NUTRTION DEFICIENCY
METABOLIC DERANGEMENTS

Question 11

SUPRAPHYSIOLOGICAL

Answer 11

HYPERTHYROIDISM
CATHECALOMINES
TACHYCARDIA

Question 12

CLINICAL FEATURES OF DILATED CARDIOMYOPATHY

Answer 12

20-50 YEARS
EJECTION FRACTION IS AROUND 25% WHILE NORMAL RANGE FROM 50-65
PROGRESSIVE CHF
ARRHYTHMIAS

Question 13

HYPERTROPHIC CARDIOMYOPATHY

Answer 13

CHRACTIRISED BY MYOCARDIAL HYPERTROPHY
POOR COMPLIANT
SYSTOLIC FUNCTION IS PRESERVED
ASSOCIATED WITH VENTRICULAR OUTFLOW OBSTRUCTION
ABNORMAL DIASTOLIC FILLING

Question 14

PATHOGENESIS OF HYPERTROPHY CARDIOMYOPATHY

Answer 14

AUTOSOMAL DOMINANT

MOST MISSENCE MUTATION

Question 15

PATHOGENESIS OF HYPERTROPHY CARDIOMYOPATHY

Answer 15

REDUCED STROKE VOLUME DUE TO IMPAIRED DIASTOLIC FILLING
OBSTRUCTION IN VENTRICULAR OUTFLOWDYSPNEA
ANGINA
ATRIAL FIBRILLATION
HARSH SYSTOLICEJECTION
MITRAL LEAF MOVE TOWARDS SEPTUM
MOST COMMON CAUSE OF DEATH

Question 16

RESTRICTIVE OF CARDIOMYOPATHY

Answer 16

SYSTOLIC FUNCTION IS PRESEVED
VENTRICULAR COMPLIANCE
CAN BE IDIOPATHIC
CAUSED BY AMYLOIDOSIS
METASTATIC TUMOURS
DEPOSITION OF METABOLITES THAT ACCUMULATES DUE TO INBORN ERRORS OF METABOLISM