Anat Path Flashcards

0
Q

How May endometriosis arise?

A
  • retrograde spread through Fallopian tubes
  • implantation during c-section
  • metaplasia
  • lymphatic spread
  • blood spread
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1
Q

Definition of endometriosis

A
  • presence of endometrium in ectopic sites
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2
Q

Complications of endometriosis

A
  • infertility
  • adhesions
  • intermittent intestinal obstruction
  • endometriod carcinoma
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3
Q

Macroscopic types of invasive cervical Ca

A
  • ulcerative
  • exophytic
  • nodular
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4
Q

Causes of death in cervical Ca

A
  • renal failure
  • haemorrhage
  • superadded infection
  • blood borne metastasis
  • iatrogenic
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5
Q

What to look at in colposcopy

A
  • margin of lesion
  • colour of lesion
  • arrangement of superficial blood vessels
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6
Q

Effects of leiomyomas

A
  • menstrual disturbance
  • infertility
  • repeated abortions
  • obstetric complications
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7
Q

Definition of hypersplenism

A

Association between peripheral blood pan cytopenia and splenic enlargement

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8
Q

Causes of secondary hypersplenism

A
  • congestion
  • infection
  • immune disorders
  • red blood cell abnormalities
  • neoplasms
  • storage disorders
  • amyloidosis
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9
Q

What may cause local thrombosis in splenic infarction?

A
  • sickle cell anaemia
  • myeloproliferative disorders
  • malignant infiltrates
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10
Q

Histology of infectious granulomatous lymphadenitis

A
  • follicular hyperplasia
  • adjacent granulomas
  • marginal zone B-cell hyperplasia
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11
Q

Histology of necrotizing lymphadenitis

A

Stellate abscesses within lymph nodes

Surrounded by palisaded histiocytes

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12
Q

Morphology of Reed-Sternberg cells

A
  • large with multi lobated or bilobed nucleus
  • very large eosinophilic nucleoli
  • slightly acidophillic cytoplasm
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13
Q

How are Hodgkin diseases classified

A
  • type and number of neoplastic cells present
  • pattern of fibrosis
  • proportion of reactive lymphocytes to neoplastic cells
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14
Q

Nucleus of nodular lymphocyte predominant HD

A

Popcorn (large folded multi lobated nucleus)

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15
Q

Complications of HD

A
  • infection
  • cachexia
  • massive organ infiltration
  • complications of treatment