Anat Path Flashcards
How May endometriosis arise?
- retrograde spread through Fallopian tubes
- implantation during c-section
- metaplasia
- lymphatic spread
- blood spread
Definition of endometriosis
- presence of endometrium in ectopic sites
Complications of endometriosis
- infertility
- adhesions
- intermittent intestinal obstruction
- endometriod carcinoma
Macroscopic types of invasive cervical Ca
- ulcerative
- exophytic
- nodular
Causes of death in cervical Ca
- renal failure
- haemorrhage
- superadded infection
- blood borne metastasis
- iatrogenic
What to look at in colposcopy
- margin of lesion
- colour of lesion
- arrangement of superficial blood vessels
Effects of leiomyomas
- menstrual disturbance
- infertility
- repeated abortions
- obstetric complications
Definition of hypersplenism
Association between peripheral blood pan cytopenia and splenic enlargement
Causes of secondary hypersplenism
- congestion
- infection
- immune disorders
- red blood cell abnormalities
- neoplasms
- storage disorders
- amyloidosis
What may cause local thrombosis in splenic infarction?
- sickle cell anaemia
- myeloproliferative disorders
- malignant infiltrates
Histology of infectious granulomatous lymphadenitis
- follicular hyperplasia
- adjacent granulomas
- marginal zone B-cell hyperplasia
Histology of necrotizing lymphadenitis
Stellate abscesses within lymph nodes
Surrounded by palisaded histiocytes
Morphology of Reed-Sternberg cells
- large with multi lobated or bilobed nucleus
- very large eosinophilic nucleoli
- slightly acidophillic cytoplasm
How are Hodgkin diseases classified
- type and number of neoplastic cells present
- pattern of fibrosis
- proportion of reactive lymphocytes to neoplastic cells
Nucleus of nodular lymphocyte predominant HD
Popcorn (large folded multi lobated nucleus)