Anaphylaxis

Question 1

Definition of anaphlaxis

Answer 1

Skin Rash +
Cardiovascular, Respiratory or Severe GI sx

OR

Acute onset of hypotension, bronchospasm, upper A/way obstruction

Question 2

Adrenaline Administration

Answer 2

1:1000 IM Adrenaline 0.01mg/kg –> upto 0.5mg
Repeat every 5mins
[See chart]

Question 3

Adrenaline Autoinjector for
1/ 10-20kg (1-5 yr olds)
2/ >20kg (5 yr olds)
3/ Pregnant women

Answer 3

1/ 0.15mg
2/ 0.3mg
3/ 0.3mg

Question 4

Ways to minimise death in people with history of anaphylaxis

Answer 4

Avoid Triggers 
Control asthma (poorly controlled asthma → assoc’d with higher mortality) 
Autoinjector 
→ carry with at all times
→ know how to use it 
→ uptodate action plan 
After administration 
→ Lay down or sit up DON’T walk or stand

Question 5

What’s the PBS criteria for autoinjection?

Answer 5

–> Patient must have been assessed to be at significant risk of anaphylaxis by, or in consultation with a;

Clinical immunologist OR
Allergist OR
Paediatrician OR
Respiratory Physician

–> Patient must have been discharged from hospital or an emergency department after treatment with adrenaline for acute allergic reaction with anaphylaxis.