Anaphylaxis

Question 1

What are the etiologies anaphylaxis?

Answer 1

• Drugs
• Latex
• Stinging Insects
• Foods
• Exercise
• Idiopathic

Question 2

How many deaths are reported each year due to stinging insects?

Answer 2

40

Question 3

Of the 40 deaths reported each year what percentage are adults?

Answer 3

3%

Question 4

What is associated with the rapid infusion of Vancomycin?

Answer 4

Red Man Syndrome

Question 5

What is the Adult dose of Epinephrine?

Answer 5

0.3-0.5 ml/mcg 1:1000

Question 6

What is the Pediatriac dose of Epinephrine?

Answer 6

0.15 ml/mcg 1:1000

Question 7

How often is Epi repeated if needed?

Answer 7

every 3-5 minutes

Question 8

What is the only contraindication to giving Epi?

Answer 8

there are no contraindications

Question 9

What is defined as the triggered appearance of one or more associated systemic signs and symptoms that are usually responsive to epinephrine?

Answer 9

Anaphylaxis

Question 10

How are anaphylaxis and anaphylactoid reactions differentiated?

Answer 10

• Anaphylaxis - is IgE mediated

- Anaphylactiod - anything other than IgE mediated

Question 11

what are the subset of antigen that bind to circulating IgE antibodies and cause and allergic reaction?

Answer 11

Allergens

Question 12

What is the disorder characterized by and overabundance of mast cells that carries an increased risk of anaphylaxis?

Answer 12

Mastocytosis

Question 13

What are common signs and symptoms of anaphylaxis

Answer 13

• Nasal Sneezing
• Congestion
• Edema
• Hoarness
• Loss of Consciousness
• Hives
• Disorientation
• Hypotension
• Weak and Rapid Pulse
• Constriction of the Airway

Question 14

What is the drug of choice for treating anaphylaxis

Answer 14

Injectable Epinephrine