Anaphylaxis Flashcards
Allergens cause
The release of antibodies which are made by B cells
Antibodies release
IGE enzymes
Which cause
Mast cells + basophils to release histamine
Which causes
Vasodilation plus shifting of fluid out of the vasculature
This leads to second exposure
Causes the release of trillions more mast cells + basophils
Then histamine
Triggers, other cells release histamine
Anaphylaxis is a
Hypereactitvy disorder
SIRS
Systemic inflammatory response syndrome
The body’s reaction to shock
Must meet 2 criteria’s
SIRS criteria
Temp under 36 degrees or temp over 38
Heart rate over 90
Breathing rate over 20 Breaths per minute
Accounts for how many deaths a year
400-800
3%
4 sources
Absorption
Inhalation
Ingestion
Injection
How many body system
2 or more
Treatment
Epi
Vent Atrovent
X2 large bore Ivs
Vital every 5
Fluid bolus, Pan hour 20 cc per kilogram times two max
Happy may be delayed to
Slower absorption due to shock