An Integrative Approach to Psychopathology Flashcards

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1
Q

_____, a degenerative brain disease that appears in early to middle age, usually the early 40s. This disease has been traced to a genetic defect that causes deterioration in a specific area of the brain, the basal ganglia. It causes broad changes in personality, cognitive functioning, and, particularly, motor behavior, including involuntary shaking or jerkiness throughout the body.

A

Huntington’s disease

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2
Q

_____, which can result in intellectual disability (previously called “mental retardation”). This disorder, present at birth, is caused by the inability of the body to metabolize (break down) phenylalanine, a chemical compound found in many foods. Like Huntington’s disease, _____ is caused by a defect in a single gene, with little contribution from other genes or the environmental background.

Neurological problems that may include seizures. Skin rashes (eczema)

A

Phenylketonuria (PKU)

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3
Q

In _____ studies, scientists study individuals who have the same disorder, such as bipolar disorder, and also share other features, such as eye color; because the location of the gene for eye color is known, this allows scientists to attempt to “link” known gene locations (for eye color, in this example) with the possible location of a gene contributing to the disorder.

A

linkage

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4
Q

According to this _____ model, individuals inherit tendencies to express certain traits or behaviors, which may then be activated under conditions of stress.

A

diathesis–stress

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5
Q

_____ correlation model or reciprocal _____ model. Some evidence now indicates that genetic endowment may increase the probability that an individual will experience stressful life events.

For example, people with a genetic vulnerability to develop a certain disorder, such as blood–injection–injury phobia, may also have a personality trait—let’s say impulsiveness— that makes them more likely to be involved in minor accidents that would result in their seeing blood. In other words, they may be accident prone because they are continually rushing to complete things or to get to places without regard for their physical safety.

A

Gene–environment

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6
Q

Neither nature (genes) nor nurture (environmental events) alone, but rather a _____ of the two, influences the development of our behavior and personalities.

A

complex interaction

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7
Q

The human nervous system includes the central nervous system, consisting of the brain and the spinal cord, and the _____, consisting of the somatic nervous system and the autonomic nervous system.

The _____has three basic functions: (1) motor commands to all voluntary striated muscles; (2) sensory information about the external world and the body to the brain and spinal cord (except visual information: the optic nerves, which convey information from the retina to the brain, are in fact outgrowths from the brain); and (3) regulating autonomic functions such as blood pressure or sweating.

Most polyneuropathies impair all three types of _____ function, although disorders selectively affecting motor, sensory, or autonomic functions occur.

A

peripheral nervous system

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8
Q

The Central Nervous System

_____ have numerous receptors that receive messages in the form of chemical impulses from other nerve cells, which are converted into electrical impulses.

They function to obtain information from other cells and carry that information to the cell body

A

Dendrites

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9
Q

The Central Nervous System

The other kind of branch, called an _____, transmits these impulses to other neurons.

responsible for transmitting electrical signals to help with sensory perception and movement.

A

axon

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10
Q

The Central Nervous System

Neurons are not actually connected to each other. There is a small space through which the impulse must pass to get to the next neuron. The space between the axon of one neuron and the dendrite of another is called the _____.

A

synaptic cleft

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11
Q

The Central Nervous System

The biochemicals that are released from the axon of one neuron and transmit the impulse to the dendrite receptors of another neuron are called _____.

A

neurotransmitters

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12
Q

The Central Nervous System

The _____ is the lower and more ancient part of the brain. Found in most animals, this structure handles most of the essential automatic functions, such as breathing, sleeping, and moving around in a coordinated way.

A

brain stem

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13
Q

The Central Nervous System

The _____ is more advanced and evolved more recently.

A

forebrain

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14
Q

The Central Nervous System

The lowest part of the brain stem, the _____, contains the medulla, the pons, and the cerebellum. The hindbrain regulates many automatic activities, such as breathing, the pumping action of the heart (heartbeat), and digestion.

A

hindbrain

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15
Q

The Central Nervous System

The _____ controls motor coordination, and recent research suggests that abnormalities in the cerebellum may be associated with the psychological disorder autism, although the connection with motor coordination is not clear

A

cerebellum

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16
Q

The Central Nervous System

Also located in the brain stem is the _____, which coordinates movement with sensory input and contains parts of the reticular activating system, which contributes to processes of arousal and tension, such as whether we are awake or asleep

A

midbrain

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17
Q

The Central Nervous System

At the top of the brain stem are the _____, which are involved broadly with regulating behavior and emotion. These structures function primarily as a relay between the forebrain and the remaining lower areas of the brain stem.

A

thalamus and hypothalamus

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18
Q

The Central Nervous System

At the base of the forebrain, just above the thalamus and hypothalamus, is the _____.

motivation, emotion, learning, and memory

A

limbic system

19
Q

The Central Nervous System

The _____, also at the base of the forebrain, include the caudate (tailed) nucleus. Because damage to these structures may make us change our posture or twitch or shake, they are believed to control motor activity.

responsible primarily for motor control, as well as other roles such as motor learning, executive functions and behaviors, and emotions.

A

basal ganglia

20
Q

The Central Nervous System

The largest part of the forebrain is the _____, which contains more than 80% of all neurons in the central nervous system.

consciousness, thought, emotion, reasoning, language, and memory.

A

cerebral cortex

21
Q

The Central Nervous System

Each _____ consists of four separate areas, or lobes: temporal, parietal, occipital, and frontal.

A

hemisphere

22
Q

The Central Nervous System

The _____ lobe is associated with recognizing various sights and sounds and with long-term memory storage.

A

temporal

23
Q

The Central Nervous System

The _____ lobe is associated with recognizing various sensations of touch and monitoring body positioning.

A

parietal

24
Q

The Central Nervous System

The _____ lobe is associated with integrating and making sense of various visual inputs

A

occipital

25
Q

The Central Nervous System

The _____ lobe is the most interesting from the point of view of psychopathology. The front (or anterior) of the frontal lobe is called the prefrontal cortex, and this is the area responsible for higher cognitive functions such as thinking and reasoning, planning for the future, as well as long-term memory. This area of the brain synthesizes all information received from other parts of the brain and decides how to respond.

A

frontal

26
Q

The _____ coordinates with the brain stem to make sure the body is working properly.

A

The Peripheral Nervous System

27
Q

The Peripheral Nervous System

Its two major components are the _____.

A

The somatic nervous system controls the muscles, so damage in this area might make it difficult for us to engage in any voluntary movement, including talking.

The autonomic nervous system includes the sympathetic nervous system and parasympathetic nervous system. regulates involuntary

28
Q

The Peripheral Nervous System

Its two major components are the _____.

A

The somatic nervous system controls the muscles, so damage in this area might make it difficult for us to engage in any voluntary movement, including talking.

The autonomic nervous system includes the sympathetic nervous system and parasympathetic nervous system. regulates involuntary

29
Q

The Peripheral Nervous System

The _____ works a bit differently from other systems in the body. Each endocrine gland produces its own chemical messenger, called a hormone, and releases it directly into the bloodstream.

A

endocrine system

30
Q

The Peripheral Nervous System

The _____ produce epinephrine (also called adrenaline) in response to stress, as well as salt-regulating hormones;

A

adrenal glands

31
Q

The Peripheral Nervous System

the _____ gland produces thyroxine, which facilitates energy metabolism and growth;

A

thyroid

32
Q

The Peripheral Nervous System

the _____ is a master gland that produces a variety of regulatory hormones;

A

pituitary

33
Q

The Peripheral Nervous System

and the _____ glands produce sex hormones such as estrogen and testosterone.

A

gonadal

34
Q

The Peripheral Nervous System

The cortical part of the adrenal glands also produces the stress hormone cortisol. This system is called the _____, or HPA axis

A

hypothalamic–pituitary–adrenocortical axis

35
Q

We can introduce substances called agonists that effectively increase the activity of a _____ by mimicking its effects; substances called antagonists that decrease, or block, a _____; or substances called inverse agonists that produce effects opposite to those produced by the _____.

A

Neurotransmitters

36
Q

Neurotransmitters
Amino-acid neurotransmitters

Scientists have discovered that a particular class of drugs, the _____, or minor tranquilizers, makes it easier for GABA molecules to attach themselves to the receptors of specialized neurons. Thus, the higher the level of _____, the more GABA becomes attached to neuron receptors and the calmer we become (to a point).

_____ are a type of sedative medication. This means they slow down the body and brain’s functions. They can be used to help with anxiety and insomnia (difficult getting to sleep or staying asleep).

A

benzodiazepines

37
Q

Neurotransmitters
Monoamine neurotrasmitters

The _____ system regulates our behavior, moods, and thought processes. Extremely low activity levels of serotonin are associated with less inhibition and with instability, impulsivity, and the tendency to overreact to situations.

Low _____ activity has been associated with aggression, suicide, impulsive overeating, and excessive sexual behavior.

A

serotonin

38
Q

Neurotransmitters
Monoamine neurotrasmitters

The class of drugs called _____, including fluoxetine (Prozac), affects serotonin more directly than other drugs, including the tricyclic antidepressants.

_____ are used to treat a number of psychological disorders, particularly anxiety, mood, and eating
disorders.

A

selective-serotonin reuptake inhibitors (SSRIs)

39
Q

Neurotransmitters

_____ has been implicated in the pathophysiology of schizophrenia and disorders of addiction, depression and attention deficit
hyperactivity disorder.

wonder drug reserpine that reduced psychotic behaviors associated with schizophrenia? This drug and more modern antipsychotic treatments affect a number of neurotransmitter systems, but their greatest impact may be that they block specific _____ receptors, thus lowering dopamine activity.

_____ switches on is the locomotor system, which regulates ability to move in a coordinated way and, once turned on, is influenced by serotonin activity. Because of these connections, deficiencies in dopamine have been associated with disorders such as Parkinson’s disease, in which a marked deterioration in motor behavior includes tremors, rigidity of muscles, and difficulty with judgment

A

Dopamine

40
Q

Neurotransmitters

_____ science, which is concerned with how we acquire and process information and how we store and ultimately retrieve it (one of the processes involved in memory)

A

Cognitive

41
Q

Neurotransmitters

_____, observed that organisms do not have to experience certain events in their environment to learn effectively. Rather, they can learn just as much by observing what happens to someone else in a given situation. This fairly obvious discovery came to be known as modeling or observational learning.

A

Albert Bandura

42
Q

Neurotransmitters

According to the concept of _____ learning, we have become highly prepared for learning about certain types of objects or situations over the course of evolution because this knowledge contributes to the survival of the species.

A

prepared

43
Q

Neurotransmitters

Emotion scientists now agree that emotion is composed of three related components—

A

behavior, physiology, and cognition.

44
Q

The principle of _____ is used in developmental psychopathology to indicate that we must consider a number of paths to a given outcome.

_____ refers to how different early experiences in life (e.g., parental divorce, physical abuse, parental substance abuse) can lead to similar outcomes (e.g., childhood depression). In other words, there are many different early experiences that can lead to the same psychological disorder.

A

equifinality