Amniotic Fluid

Question 1

1. Reasons for analyzing amniotic fluid include the following EXCEPT:

a. To diagnose genetic and congenital neural tube disorders
b. To assess fetal liver maturity
c. To assess fetal lung maturity
d. To detect fetal distress from hemolytic disease of the
newborn

Answer 1

b. To assess fetal liver maturity

Question 2

2. The following is true about amniotic fluid specimen collection and handling:
   a. Fifty milliliters of amniotic fluid is typically collected
   b. Glass containers are used for cytogenetic studies
   c. Typical amniotic fluid is colorless to pale yellow and slightly cloudy
   d. Amniotic fluid is always refrigerated

Answer 2

c. Typical amniotic fluid is colorless to pale yellow and slightly cloudy

Question 3

3. Bilirubin is detected spectrophotometrically in amniotic fluid at:
   a. 365 nm
   b. 550 nm
   c. 410 nm
   d. 450 nm

Answer 3

d. 450 nm

Question 4

4. A potential complication caused by early delivery of the premature newborn:
   a. Hemolytic disease of the newborn
   b. Neural tube defects
   c. Respiratory distress syndrome
   d. Excess lamellar bodies

Answer 4

c. Respiratory distress syndrome

Question 5

5. All of these phospholipids have a role in fetal lung maturity EXCEPT:
   a. Lecithin
   b. Sphingomyelin
   c. Phosphatidylglycerol
   d. Lamellar bodies

Answer 5

b. Sphingomyelin

Question 6

6. A M450 value that falls into zone I indicates:
   a. A normal finding without significant hemolysis
   b. Moderate hemolysis
   c. Severe hemolysis
   d. High fetal risk

Answer 6

a. A normal finding without significant hemolysis

Question 7

7. Decreased fetal swallowing can result in:
   a. Hydraminos
   b. Hydronephosis
   c. Oligohydramnios
   d. Oligohyponephrosis

Answer 7

a. Hydraminos

Question 8

8. Amniocentesis is performed:
   a. Through the umbilicus
   b. Transabdominally
   c. Transvaginally

Answer 8

b. Transabdominally

Question 9

9. Which test is most specific for neural tube disorders?
   a. Acetylcholinesterase
   b. Alpha fetoprotein
   c. Phosphatidyl glycerol
   d. Lecithin to sphingomyelin ratio

Answer 9

b. Alpha fetoprotein

Question 10

1 0. Which test on amniotic fluid can aid in the diagnosis of
HDN?
a. Alpha fetoprotein
b. Bilirubin
c. Phosphatidylglycerol
d. Surfactant

Answer 10

b. Bilirubin

Question 11

11. The Kleihauer-Betke test is for:
    a. Alpha fetoprotein
    b. Fetal hemoglobin
    c. Phosphatidylglycerol
    d. Maternal hemoglobin

Answer 11

b. Fetal hemoglobin

Question 12

12. Which lecithin:sphingomyelin ratio indicates fetal lung maturity?
    a. Equal to or less than 0.5
    b. Less than 1 .0
    c. Less than 2.0
    d. Equal to or greater than 2.0

Answer 12

d. Equal to or greater than 2.0