Amnesia Flashcards
describe the case of clive wearing
‘7sec memory’
viral brian infection - severe retrograde and anterograde amnesia
everyday is first day
concert pianist - can play but doesnt know about it
describe the case of patient HM
surgery to prevent epilepsy - remove bilateral hippocampus in temp lobes
severe anterograde amnesia and some retrograde
short term and intelligence unimpaired
cant recognise familiar faces, read same mag over and over, perform old skills
earliest memory at 11yrs
but - some memories survive w/o hippocampus - consolidation
define retrograde amnesia
unable to recall events that occurred before the development of the amnesia, even though they may be able to encode and memorize new things that occur after the onset.
define anterograde amnesia
loss of the ability to create new memories after the event that caused the amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.
describe karsakoff syndrome
alcoholism - thiamine deficiency and brain damage
abnormalities in diencephalon - incorporates hypothallamus
- antero/retrograde amnesia
cause confabulation due to frontal lobe damage
define confabulation
incorporation of false memory into own memory
describe Huppert and Piercy (1978)
amnesic subjects with karsakoff consistently reported to forget at a normal rate whereas patients with medial temporal lobe damage reported to forget pathologically fast.
got karsakoff at same baseline recog level as control
%correct in line with control - amnesia not due to forgetting very fast
must be due to how memory is stored
describe cowan, beschin, and dellasalla (2004) retroactive
ask controls and amnesia to recall story immediately or after delay
delay - interference or no interference
interference reduce in both amnesia and control BUT amnesia sig more
little memory of recall
interference impairs memory
what abilities can amnesiacs maintain
7+/- 2 STM most anterograde norm performance on digit span recency effect preserved BUTsig poorer primacy can still be conditioned ie eye blink prev skills ie clive piano
describe claparede (1911) conditioning amnesiacs
drawing pin prick and shaking amnesiac hand
secon meeting - not remember doctor but dont know why doesnt want to shake hand
carmack and o’connor (1888) prev skills
c&oc - laser spcialist - amnesia but still do job well
describe squire et al (1993)
expose to priming word “alligator”
sig faster at completing puzzle word “c_o_o_i_e” (crocodile)
describe glisky schacter and tulving (1986)
method of vanishing cues
systematic reduction of letter fragments of to-be-learned words across trials
able to produce the target words in the absence of fragment cues
retained the vocabulary over a 6-week interval
how can amnesia inform us on how memory works
support and cast doubt on memory models
double disossiations - can have intact LTM and impaired STM and vise versa
evidence for the division between the two (support at and shriff)
describe atkinson and shriffin
STM <M -
episodic vs semantic
declarative vs procedural
implicit vs explicit
LTM - declarative/explicit - epsodic or semantic
-non declar/implicit - procedural, priming or conditioning
define episodic
autobio, time based
define semantic
ideas, concepts, common knowledge
define procedural
subset of implicit memory
what can do - sensorimotor tasks
memory of skills/how to do things
define declarative
subset of explicit memory
what can say
facts etc
split into episodic and semantic
define implicit
unconscious
define explicit
conscious
describe Tulving (1989)
episodic vs semantic memory
amnesia studies better memory for facts than episodes
facts likely to be learnt before amnesia
what does research suggest about episodic and semantic memory
partially dissociated
episodic - full dependence on hippocampus
semantic - support by sub-hippocampal structures
amnesiacs likely to have damage to both
describe cohen and squire (1980) decl and proc
delarative vs procedural memory
amnesiac difficult form declarative mem but not non decl/rpocedural ie motor skill usually maintained
describe schatt et al (2005)
found activation in different regions of the brain dependent on a declarative or procedural task
but - many skills require both
describe chun and phelps (1999)
visual search tasks for amnesiacs and cotnrol
search for T in Ls
given only display or new changed display each time
control - improve skill and sig better in old
amnesia - improve skill but no better in old (always new to them)
hippocampus binds info - can do implicit tasks as long as doesnt involve binding
define binding
integration of info and skills
limitations of amnesia studies
hard to tell onset and trajectory of amnesia as develop over time
causes unique
cases unique - diff location, extent etc
no average level pre-amnesia to compare to