Aminoglycosides

Question 1

What are Aminoglycosides?

Answer 1

Big gun antibiotics.

Treat serious, life threatening, resistant infections

Question 2

All aminoglycosides end in?

Answer 2

“mycin” Vancomycin

Question 3

For Aminoglycosides, think:

Answer 3

A Mean Old Mycin

Question 4

If it has “thro” in it you?

Answer 4

Throw it out…Zithromycin.

It treats a minor infection

Question 5

Toxic effects of aminoglycosides?

Answer 5

Ototoxicity
Nephrotoxicity
Cranial nerve 8 (vestibulocochlear nerve) which senses sound.

Question 6

The one Aminoglycoside that doesn’t end in Mycin?

Answer 6

Amikacin

Question 7

What is another word for aminoglycoside?

Answer 7

Glycopeptide

Question 8

In aminoglycoside use monitor?

Answer 8

Hearing, balance, tinnitus & creatinine (best indicator of renal function)

Question 9

If you have to pick which side effect/assessment you do first, pick

Answer 9

Ototoxicity (Ears)

Question 10

Frequency of administration for aminoglycosides?

Answer 10

Q8H

Question 11

Aminoglycoside route of administration?

Answer 11

Im or IV

Question 12

Aminoglycosides are given PO for what 3 reasons?

Answer 12

Hepatic Encephalopathy

Pre-op bowel surgery.

C diff

Question 13

What is Hepatic Encephalopathy also called?

Answer 13

Liver Coma,

Ammonia-Induced Encephalopathy

Question 14

If fluid resuscitation is used in shock, there will be

Answer 14

Increased Urine Output

Question 15

Neomycin and Kanmycin are used for what?

Answer 15

Bowel sterilzation?

Can also be given for C.Diff

Question 16

Who can sterilize my bowel?

Answer 16

“Neo” “Kan”

Question 17

If you give aminoglycosides PO, do you have to worry about side effects?

Answer 17

No

Question 18

Hepatic Encephalopathy is caused by?

Answer 18

High ammonia levels

Question 19

What raises ammonia levels the most?

Answer 19

Ecoli in the gut

Question 20

Why do you draw TAP levels?

Answer 20

Narrow therapeutic Window

Question 21

When do you draw a trough level?

Answer 21

30 minutes before the next scheduled dose.

Question 22

When do you draw a sublingual peak level?

Answer 22

5-10 minutes after it is dissolved.

Question 23

When do you draw a IV peak level?

Answer 23

15-30 minutes after dose is finished.

Question 24

When do you draw a IM peak level?

Answer 24

30-60 minutes after given

Question 25

If you must pick a time to draw the peak, pick the highest amount of time without going over the limits

Answer 25

So for IV, Pick 30 Minutes, not 15.