Amino Acid Metabolism

Question 1

Glycine is inhibitory or excitatory

Answer 1

Inhibitory

Question 2

Glutamate is inhibitory or excitatory

Answer 2

Excitatory

Question 3

GABA aa precursor

Answer 3

Glutamate

Question 4

Histamine aa precursor

Answer 4

Histidine

Question 5

Serotonin aa precursor

Answer 5

Tryptophan

Question 6

Nitric Oxide aa precursor

Answer 6

Arginine

Question 7

Thyroid Hormone, Melanin, Dopamine, Epinephrine, Norepinephrine aa precursor

Answer 7

Tyrosine

Question 8

What is a PEST sequence?

Answer 8

Protein degradation signal consisting of PEST-rich regions

Question 9

Which N-terminal residues result in a short-lived protein?

Answer 9

Phe, Leu, Asp, Lys, Arg

RFLDK
Riffle Dick

Question 10

Which N-terminal residues result in a longer-lived protein?

Answer 10

Met, Ala, Gly, Ser, Thr, Val

MAGS TV
max TV

Question 11

Autophagy

Answer 11

Recycling of old organelles

Question 12

Phenylketonuria

Answer 12

Lack of PAH (Phenylalanine Hydroxylase) results in a lack of Tyrosine synthesis

Increase in Phe metabolites, giving urine a musty odor (PhePyr, PheLac, PheAce)

Question 13

Albinism

Answer 13

Lack of Tyrosinase to synthesize melanin

Question 14

Alkaptonuria

Answer 14

Lack of Homogentisate to break down Tyrosine, leading to black urine and severe arthritis