Amines (Lecture) Flashcards
compounds of nitrogen connected to a CARBONYL GROUP
AmiDes
Types of Amines
Primary
Secondary
Cyclic
Tertiary
ONE hydrogen atoms of the ammonia mol is replaced by an alkyl or aryl group
Primary amines
Methylamine (CH3NH2)
Aniline (C6H5NH2)
Primary amines
TWO organic substituents replace the hydrogen atoms of the ammonia molecule forming an amine
Secondary amine
Dimethylamine (CH3)2NH
Diphenylamine (C6H5)2NH
Secondary amine
all THREE of the hydrogen atoms are replaced by an organic substituent, it could be an aryl oromatic
Tertiary amines
Trimethylamine N(CH)3
Ethylendiamineeteraacetic acid EDTA
tertiary amines
The secondary or tertiary amines in an aromatic ring structure
Cyclic amines
Piperdine (CH2)5NH
Aziridines C2H5N
Cyclic amines
Formula of primary amines
RNH2
Secondary amines formula
R2NH
Tertiary amines formula
R3N
They occur in nature, principally as products of the putrefaction of protein material, but they are also present in living tissue
Aliphatic amines
Histamine is an example of
Cyclic aliphatic amine
A salt is formed by what reaction of amines
Addition
One of the most important reactions of primary and secondary amines
Acylation
A hydrogen atom is REPLACED by an acyl group
Substitution
Amines burns in air, producing water, carbon dioxide and either nitrogen or it’s oxides
Oxidation
What reaction does Hoffman degration takes place
Elimination
This is the principal reaction of quarternary ammonium compounds
Hoffman degration