Alzheimer's Dz Flashcards

1
Q

greatest risk factor

A

age (65+)

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2
Q

other risk factors

A

-family hx
-cardiovascular factors (HTN, obesity, stroke, hyperlipidemia)
-diabetes (high levels of insulin and glucose toxic to brain)
-head trauma

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3
Q

familial Alzheimer’s dz

A

-clear pattern of inheritance
-onset before age 60
-rapid dz discourse

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4
Q

sporadic alzhemiers dz has no

A

familial connection

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5
Q

where do the plaques first develop in the brain?

A

areas used for memory and cognitive function

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6
Q

what happens to brain structure and function?

A

-genetic factors
-plaque
-neurofibrillary tangles
-loss of connection between neurons
-neuron death

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7
Q

10 warning signs of AD

A
  1. memory loss
  2. difficulty performing familiar tasks
  3. problems with language
  4. disorientation to time and place
  5. poor or decreased judgement
  6. problems with abstract thinking
  7. misplacing things
  8. changes in mood or behavior
  9. changes in personality
  10. loss of initiative
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8
Q

in normal age related memory changes, a person forgets part of an experience. in Alzheimers, the pt

A

forgets entire experience

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9
Q

in normal age related memory changes, a person often remembers later. in Alzheimers, the pt

A

rarely remembers later

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10
Q

in normal age related memory changes, a person is usually able to follow written/spoken instructions. in Alzheimers, the pt

A

gradually unable to follow written / spoken direction

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11
Q

in normal age related memory changes, a person is usually able to use notes as reminders. in Alzheimers, the pt

A

gradually unable to use notes as reminders

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12
Q

in normal age related memory changes, a person is usually able to care for self . in Alzheimers, the pt

A

gradually unable to care for self

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13
Q

what is retro genesis?

A

the pt ages backwards - will go back to doing things like a child - toys, cant hold up head, etc.

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14
Q

is there a definitive test for AD?

A

no

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15
Q

what does a definitive diagnosis require?

A

autopsy

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16
Q

what things can be done to help with diagnosis?

A

-health hx
-physical, neuro, mental assessment
-lab test
-CT, MRI, PET
-mini cog
-mini mental state exam

17
Q

is there a cure for AD?

A

no

18
Q

what is care aimed at?

A

controlling undesirable behavioral manifestations and providing support for family caregiver

19
Q

memantine drug MOA

A

protects nerve cell against excess amounts of glutamate

20
Q

cholinesterase inhibitors

A

-donepezil
-rivastigmine

21
Q

antidepressants

A

-sertraline
-citalopram
-fluoxetine

22
Q

antipsychotic drugs

A

-haloperidol
-risperidone

23
Q

nursing management

A

-support cognitive function
-promote physical safety
-promote independence and self care
-reduce anxiety and agitation
-improve communication
-provide socialization
-promote adequate nutrition
-promote balanced activity and rest
-educate on home and community based assistance