Alveolar Ventilation Flashcards
Change in volume for alveoli
Greatest at units at the bottom of the lung; due to the fact that these alveoli have the smallest volume at rest due to the increased intrapleural pressure at the bottom of the thoracic cavity
Diseases w/ increased DLco
Asthma-due to uniform bloodflow
Bronchitis-only upper pathways are affected
Hemorrhage- Hb combines w/ CO to raise DLco
Intracardiac shunts
Lung Ventilation
Lower part > Top part
*Anatomically relevant to the direction of gravitational force
V/Q Units
Underventilated alveolar units due to decreased compliance of the tissue
Partial Pressure of Gases
Pa= Fa X Ptotal
Barometric Pressure
760mmHg
Partial Pressure of N2 and O2 at barometric pressure
N2= (760)(.790)=600mmHg
O2= (760)(.210)=160mmHg
Pressures of Inspired Gases
Decreased due to H20=mmHg
Inspired O2/Expired CO2
250/200
Minute Ventilation
V=Freq X Vt
Alveolar Ventilation
Va=Freq(Vt-Vd)
*This equation includes only the air ventilated into the alveoli per minute
Respiratory Exchange Ratio
Rate of CO2 output/ Rate of O2 uptake
=0.8
Anatomical Dead Space
Volume of air left in large airways
Physiological Dead Space
Anatomical Deadspace+ Alveolar Deadspace
Measurement of Physiological Dead Space
Vd/Vt=PaCO2-PeCO2/ PaCO2
Pe= Partial pressure of CO2 in expired gas
Pa= Arterial pressure of CO2