Alveolar hypoxia Flashcards
Hypoxemia defined as
resulting abnormally low oxygen concentration in the blood
Alveolar hypoxia describes
insufficient oxygen delivery to the alveoli of the lungs
In order to combat these difficulties
native sea level dwellers that move to high altitude undergo compensatory changes with alterations occuring over an extended period of time (days, months, even years)
Interestingly, native-sea dwellers that move and stay at high altitude develop…
increased pulmonary arterial pressure (PAP) in the absence of pre-existing lung disease
The primary mechanisms causing the sustained increase in PAP consist of
diffuse hypoxic pulmonary vasoconstriction (HPV) and pulmonary vascular remodelling (PVR)