Alteplase - Drug Card Flashcards

1
Q

Alteplase - Drug Class

A

thrombolytic agent

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2
Q

Alteplase - mechanism of action

A
  • degrades fibrinogen, fibrin and other clotting factors disintegrating clot
  • the clot buster
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3
Q

Alteplase - use

A
  • treat PE, thromboembolism, thrombolytic stroke
  • necrosis resulting from blocked artery
  • CLOT BUSTER
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4
Q

Alteplase - side effects

A

anaphylaxis
hemorrhage (many precautions taken due to high risk for hemorrhage)

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5
Q

Alteplase - life threatening reactions

A
  • stroke
  • dysrhythmias
  • pulmonary edema
  • kidney failure
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6
Q

Alteplase - contraindications

A

intracranial bleeding
aneurysm
CVA
Brain tumor
head trauma

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