Allergy & Immunology

Question 1

Immunoglobulin A vasculitis pathophysiology, presentation & management

Answer 1

• pathophysiology: small vessel vascuilitis of skin, GI tract, joints & kidneys
• presentation: triad of purpura, arthritis & abdominal pain, mainly in children; preceded by URI in 50% of cases
  (formerly known as Henoch-Schonlein Purpura)
• management: supportive (spontaneously resolves in 4-5 weeks)