Allergy and The Skin Flashcards
Type I
Reaction depends on…
Symptoms
Mast cell mediated
IgE involved
Previous exposure to allergen leads to histamine release
Eczema, rhinitis
Type IV
T-cell mediated
Not direct immune reaction
APC present and sensitise cells
High molecular weight allergens
Why does it cause problems
Can’t be absorbed by skin - delivered elsewhere e.g lungs and nose
Tends to cause Type I HS reactions
Low molecular weight allergens
Why does it cause issues?
Paints, dyes, metal ions
Absorbed by skin
Contact dermatitis - irritant, allergic
Caused by?
Cheilitis is a type of? Which type?
Mild reaction to gloves
Allergies to LA
Contact dermatitis
Anaphylaxis - tx
Solution is oxygen and adrenaline
a, b, adrenaline
Give .5mg