Allergy and The Skin Flashcards

1
Q

Type I

Reaction depends on…

Symptoms

A

Mast cell mediated
IgE involved

Previous exposure to allergen leads to histamine release

Eczema, rhinitis

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2
Q

Type IV

A

T-cell mediated
Not direct immune reaction
APC present and sensitise cells

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3
Q

High molecular weight allergens

Why does it cause problems

A

Can’t be absorbed by skin - delivered elsewhere e.g lungs and nose
Tends to cause Type I HS reactions

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4
Q

Low molecular weight allergens

Why does it cause issues?

A

Paints, dyes, metal ions

Absorbed by skin

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5
Q

Contact dermatitis - irritant, allergic

Caused by?

Cheilitis is a type of? Which type?

A

Mild reaction to gloves
Allergies to LA

Contact dermatitis

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6
Q

Anaphylaxis - tx

A

Solution is oxygen and adrenaline
a, b, adrenaline
Give .5mg

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