All Exam 3 Questions Flashcards

1
Q

Fish-hunting snails inject toxins into their victims that block acetylcholine receptors at the neuromuscular junction and cause muscle paralysis. The toxin is most likely blocking _______ channels

A. Voltage-gated K+
B. Ligand-gated Cl-
C. Voltage-gated Ca2+
D. Ligand-gated Na+

A

D. Ligand-gated Na+

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2
Q

When a person is not starving, _______ would be used as fuel by fast muscle fibers, whereas _______ would be used as fuel by slow muscle fibers

A. Glycogen; proteins
B. Proteins; glycogen
C. Glycogen; fats
D. Fats; glycogen

A

C. Glycogen; fats

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3
Q

_______ are white blood cells (WBC) with a multilobed nucleus which stain with a neutral dye. They arrive first at the site of injury, phagocytose bacteria, and contribute to the formation of pus

A. Basophils
B. Neutrophils
C. Monocytes
D. Eosinophils

A

B. Neutrophils

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4
Q

A mutation that inactivated the myosin light chain reaction phosphatase enzyme will likely cause the following in smooth muscles

A. Ca2+ can not bind calmodulin
B. Regulatory light chain will not be phosphorylated
C. Myosin cannot interact with actin
D. Regulatory light chain will not be dephosphorylated

A

D. Regulatory light chain will not be dephosphorylated

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5
Q

______ triggers the hematopoietic stem cells (HSCs) to develop into lymphocytes

A. Multi-CSF (Colony Stimulating Factors)
B. GM-CSF
C. M-CSF
D. None of the above

A

D. None of the above

(Triggered by cytokines)

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6
Q

The slope constructed using the end systolic volume in the PV loop indicates:

A. Afterload
B. Preload
C. Contractility
D. Ejection fraction

A

C. Contractility

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7
Q

In the heart, ______ produce action potentials spontaneously. The resulting electrical signals cause _______ to contract

A. Autorhythmic cells; cardiomyocytes
B. Myocytes; autorhythmic cells
C. Nerve cells; myocytes
D. Myocytes; nerve cells

A

A. Autorhythmic cells; cardiomyocytes

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8
Q

The ______ receives deoxygenated blood from the superior vena cava

A. Left Ventricle
B. Right ventricle
C. Left atrium
D. Right atrium

A

D. Right atrium

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9
Q

During isovolumetric contraction there is no change in volume because the ventricular pressure is _______ than the aortic pressure but _______ than the atrial pressure

A. Higher; higher
B. Lower; lower
C. Lower; higher
D. Higher; lower

A

C. Lower; higher

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10
Q

Cardinal signs of inflammation such as heat, redness, and swelling are mediated by _______ released from mast cells

A. Histamine
B. Heparin
C. Erythropoietin (EPO)
D. Interleukins

A

A. Histamine

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11
Q

Jaundice is a yellow coloration of the skin and eyes caused by a buildup of ________

A. Biliverdin
B. Urobilins
C. Stercobilins
D. Bilirubin

A

D. Bilirubin

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12
Q

The autonomic nervous system can _______ heart rate by causing greater ______ of the membrane potential of pacemaker cells

A. Increase; hyperpolarization
B. Decrease; depolarization
C. Increase; depolarization
D. More than one answer is possible

A

C. Increase; depolarization

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13
Q

Lipopolysaccharides (LPS) found on the surface of gram-negative bacteria is an example of ________, which signal the presence of pathogens to the immune system

A. Cluster of differentiation (CD) molecules
B. Pathogen associated molecular patterns (PAMPs)
C. Damage associated molecular patterns (DAMPs)
D. Cytokines

A

B. Pathogen associated molecular patterns (PAMPs)

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14
Q

An abnormal antibody is unable to bind to pathogens, but it can be recognized by macrophages. It is most likely that the abnormality in the antibody is in the ________

A. Antigen binding site
B. Heavy chains
C. Constant segments of the heavy chains
D. Constant segments of the light chains

A

A. Antigen binding site

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15
Q

Which of the following is commons to skeletal and cardiac muscles, but not to smooth muscles?

A. Actin-myosin interaction
B. Troponin-tropomyosin complex
C. Gap junctions
D. Varicosities

A

B. Troponin-tropomyosin complex

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16
Q

During an activation of a T-helper cell, the binding of interleukin 2 (IL2) to naive T cells leads to _______

A. Antigen recognition
B. Clonal expansion/proliferation
C. Co-stimulation
D. Antibody recognition

A

B. Clonal expansion/proliferation

17
Q

Cardiac output (CO) is the volume of blood pumped through the circulatory system in 1 minute (ml/min). Therefore, CO is inversely associated with ________

A. End systolic volume
B. End diastolic volume
C. Heart rate
D. Stroke volume

A

A. End systolic volume

18
Q

During rigor mortis, myosin heads remain bound to actin because ________

A. SERCA pumps are functioning correctly
B. ATP is unavailable to bind myosin
C. Ryanodine receptors cannot function
D. Calcium is unavailable to activate the thin filaments

A

B. ATP is unavailable to bind myosin

19
Q

If you want to study how lymphocytes are formed and mature, ,you would likely harvest cells from primary lymphoid organs such as _______

A. Lymph nodes
B. Tonsils
C. Bone marrow
D. Spleen

A

C. Bone marrow

19
Q

Abnormal T waves in an EKG can MOST LIKELY be indicative of defects in ________

A. Ventricular systole
B. Atrial systole
C. Ventricular diastole
D. None of the above

A

C. Ventricular diastole

20
Q

Ca2+ binding to troponin C subunits permits the thin filament to transition from the ________ state.

A. Blocked to closed
B. Closed to open
C. Open to closed
D. Open to blocked

A

A. Blocked to closed

21
Q

The cardiac muscle is ______ sensitive to changes in muscle length than the skeletal muscle because it functions in the ______ of the force-length relationship

A. Less; descending limb
B. More; plateau
C. More; ascending limb
D. Less, ascending limb

A

C. More; ascending limb

22
Q

isotonic concentric contraction occurs when you:

A. Raise a dumbbell by flexing the arm
B. Lower a dumbbell by extending the arm
C. Hold a dumbbell in place
D. None of the above

A

A. Raise a dumbbell by flexing the arm

23
Q

The rapid depolarization of the pacemaker cells is due to:

A. Ca2+ channels
B. Na+ channels
C. HCN channels
D. K+ channels

A

A. Ca2+ channels

24
Q

Which of the following permits the maximum exchange of substances by slowing blood flow to the greatest extent

A. Elastic arteries
B. Veins
C. Arterioles
D. Muscular arteries

A

C. Arterioles

25
Q

A person with an RQ value of 1.0 is most likely:

A. Resting
B. Using glucose to make ATP
C. Exercising vigorously for 5 seconds
D. Using fats to make ATP

A

B. Using glucose to make ATP

26
Q

Which of the following pathological outcomes can occur rapidly and without warning?

A. heart attack
B. Cardiac arrest
C. Atherosclerosis
D. Coronary artery disease

A

B. Cardiac arrest

27
Q

Which of the following cells are most directly responsible for innate immunity?

A. Plasma cells
B. Memory cells
C. Macrophages
D. B lymphocytes

A

C. Macrophages