ALL Flashcards
1
Q
What is ALL?
A
malignant proliferation of lymphoid blasts in blood and bone marrow
2
Q
How is ALL classified?
A
By immunophenotype (B vs T)
3
Q
Who is ALL most common in?
A
Children
4
Q
Prognosis of ALL?
A
Often good!
5
Q
ALL and TdT
A
all are TdT+
6
Q
T lineage
A
worse prognosis
7
Q
B lineage
A
better prognosis
8
Q
T lymphoblastic leukemia =
A
T lymphoblastic lymphoma
9
Q
Who does T lymphoblastic leukemia present in?
A
Teenage boys, mediastinal mass (Think THYMUS)
10
Q
WBC and T lymphoblastic leukemia?
A
WBC often VERY HIGH
11
Q
B lymphoblastic leukemia =
A
b lymphoblastic lymphoma
12
Q
Rarely, what chromosome does B lymphoblastic leukemia have?
A
Philadelphia
13
Q
Immunophenotype and Prognosis
A
T is bad, B is better
14
Q
Age and Prognosis
A
1 - 10 years old very good
15
Q
WBC and Prognosis
A
better if
