All Flashcards
Brain stem includes…
mid brain, pons, medulla oblongata
Midbrain function
pain suppression, reticular formation
- degeneration of substantia nigra leads to Parkinson’s disease
Cerebellum function
balance, proprioception, body position/posture, coordination
- vermis instead of fissure that separates hemispheres
Meninge layers
dura mater, arachnoid mater, pia mater
Dura mater (outermost)
periosteal layer, meningeal layer, flax cerebra, flax cerebelli, tentorium (transverse fissure), epidural space, subdural space
Arachnoid mater (middle)
subarachnoid space
Cerebral Spinal Fluid (CSF)
- protects brain/spinal fluid
- ependymal cells (neuroglia cells)
Stimulus binds to…
the receptor
channel opens…
allows ions to get in
local depolarization
local depolarization of the muscle cell plasma membrane opens voltage-gated Na+ channels in this membrane, allowing more Na+ to enter, which further depolarizes the membrane
Peripheral Nervous System (PNS)
- Sensory receptors; specific
- Sensory (afferent) fibers
- Motor (efferent) fibers
- Ganglion; cluster of neurosomas outside CNS
- Nerves exit vertebral canal through intervertebral foramen
Mechanoreceptors
touch, sound, vibration
Thermoreceptors
temperature
Photoreceptors
light, sight
Chemoreceptors
sense changes in the chemical composition of the blood
Nociceptors
pain
Exteroceptors
mechanoreceptors, thermoreceptors
Intereceptors
chemoreceptors, mechanoreceptors, thermoreceptors
Proprioceptors
mechanoreceptors
General receptors
touch, pressure, stretch, vibration
Special receptors
taste, vision, smell, hearing
Sensation vs. Perception
Sensation (gets stimulated) awareness of changes in environment
Perception (conscious interpretation): what you do with stimulus
Dorsal root
- Ganglion (bulge); brings towards brain (afferent)
- Sensory fibers
- Afferent
Anterior/ventral root
- Motor fibers
- Efferent
Mixed nerves are…
both sensory and motor fibers
Sensory (afferent) nerves have impulses only…
toward CNS
Motor (efferent) nerves have impulses only…
away from CNS
Ganglia
autonomic motor neurons
reflex
autonomic response
31 pairs of spinal nerves
- Spinal nerves exit underneath their likewise vertebrae
- Each spinal nerve connects to spinal cord via two roots
Intervertebral canal vs. Intervertebral foramen
Canal: spinal cord (donuts on top of each other)
Foramen: spinal nerves go out
Somas make…
gray matter
Axons make…
white matter
Nerve plexuses
- Contains fibers from several different spinal nerves
- Each limb muscles innervated by more than one
Cervical Plexus
C1 – C4
- Most form cutaneous nerves
- Phrenic nerve C3-C5
Brachial Plexus
C5 – C8, T1
- Axillary nerve
Lumbar Plexus (lumbosacral plexus)
L1 – L4
- Femoral nerve
- Obturator nerve
Sacral Plexus (lumbosacral plexus)
L4 – S4
- Sciatic nerve
- Composed of two nerves; tibial and common fibular
Dermatomes
- Map of jurisdiction
- Nerve will innervate specific area from specific sensory information
Reflexes are…
- Quick
- Involuntary
- Stimulation
- Intrinsic = inborn
- Acquired = learned
Reflec Arc
- Receptor
- Sensory neuron
- Integration center
- Motor neuron
- Effector
Somatic reflexes
interneuron makes signal
activate skeletal muscle
Mediated by spinal cord
quick, cannot wait for brain
Stretch and flexor
Autonomic reflexes
activate visceral effectors (smooth/cardiac muscle)
Tendon organs
senses tension on tendon
triggers the reflex
proprioceptor: responds to excessive tension (muscle contraction response)
Nerve pathway
- Dorsal
- Interneuron
- Ventral
- Effector
Flexor reflex
Flexes joint
Crossed extension reflex
- Contraction of opposite limb that is not flexing (i.e. one leg is flexing, the other is contracting)
- Helps keep balance
Superficial reflexes
- Gentle cutaneous stimulation
- Plantar reflex L4-S2
- Abdominal reflex T8-T12
Spinal cord
conduction
integration
locomotion
reflexes
protected by meninges
cauda equina
Conduction
the transmission of excitation through living tissue and especially nervous tissue. conduction of impulses to the brain
Integration
input and elicited response
Locomotion
repetitive coordinated contractions
Reflexes
involuntary responses to stimuli
Meninges
dura, arachnoid, pia
Cauda equina
Nerve roots at end of spinal cord
Ascending
up, sensory
Descending
down, motor
Transverse
both ascending, descending
Contralateral
opposite side
Decussation points
when fiber crosses to other side
Ipsilateral
same side
First-order neuron
sensory neuron
- Detect stimulus from skin
- Stimulus to spinal cord
Second-order neuron
integration neuron
- In thalamus
Third-order neuron
motor neuron
- From thalamus to cortex
Descending tracts…
carry motor
Upper motor neuron
cortex
Lower motor neuron
brain stem/spinal cord
Cranial nerves
12 -
1. Olfactory
2. Optic
3. Oculomotor
4. Trochlear
5. Trigeminal
6. Abducens
7. Facial
8. Vestibulocochlear
9. Glossopharyngeal
10. Vagus
11. Accessory
12. Hypoglossal
Cranial nerves mnemonic
Oh oh oh take the anatomy final very good vacation sounds heavenly
Cranial nerves (sensory/motor/both)
Sensory:
Olfactory
Optic
Vestibulocochlear
Motor:
Oculomotor
Trochlear
Abducens
Accessory
Hypoglossal
Both:
Trigeminal
Facial
Glossopharyngeal
Vagus
Cranial nerves (sensory/motor/both) mnemonic
Some say marry money but my brother says big brains matter more
Merocrine
exocytosis
Apocrine
loses part of cell
Holocrine
celll dies completely
diaphoresis
sweat that you see
perspiration
sweat that you don’t see
How many layers does dermis have? What are they called?
2 layers; papillary and reticulum
Papillary layer of dermis
upper, attached to basement membrane
Reticulum layer of dermis
lower, attached to fat/hypodermis
Apoptosis
no inflammation
Afferent
Arrives
Efferent
Exits
Kidney: A WET BED
A – acid balance
W – water balance
E – electrolyte balance
T – toxin removal
B – blood pressure control
E – Erythropoietin making
D – Vitamin D metabolism
Layers of skin (from outermost to innermost)
- Corneum
- Lucidum
- Granulosum
- Spinosum
- Basal
Bone matrix
ossification
osteoporosis
pores in bone get bigger
Three types of cartilage
elastic, hyaline, fibrocartilage
Elastic cartilage
external ear and epiglottis
Fibrocartilage
meniscus of knee, vertebral disc, pubic symphysis
Hyaline cartilage
many joint surfaces
most commonly found in the ribs, nose, larynx, and trachea
Appositional growth
chondroblasts grow into chondrocytes
- Grows in thickness
- B after A
Interstitial growth
existing chondrocytes
- C after B
Bone formation
- Baby no need for cartilage (osteoblasts build it)
- Trap blood vessels
- Becomes spongy bone
Bone formation
- Starts in diaphysis
- Grows towards island in poles
- Growth plates have closed
Blast
Blast, baby, build
Cyte
Cyte, adult, maintain
Clast
Clast, cut, release calcium to blood
Genic
origin
Osteon
function instructional unit of skeletal system
Lacuna
Cyte
no babies in a jacuzzi
Lamellae
concentric layers
Lacunae
holes
Canaliculi
tiny tunnels connecting cells together
Periosteum
outside
Endosteum
inside
Chondro
cartilage
Epiphysial plate
child/open
Epiphysial line
adult/fused
Storage of calcium
- Pack calcium when there’s an excess of calcium in the blood
- Release/take out when calcium needed elsewhere
- Hormones = messengers
Minerals/vitamins
crucial for function of skeletal system
Excessive loss/low levels of vitamin D
- Osteoporosis, rickets (child), osteomalacia (adult)
Acromegaly
too much bone
Axial skeleton
Skull and vertebral column
- C1 vertebrae doesn’t have a body
- C2 vertebrae has a dens as a body
Clavicle
- Medial sternal
- Middle middle
- Lateral outside/acromial
Capitulum
lateral, articulates with radius
Trochlea
medial, articulates with ulna
Fossa
stops for the bone
Posterior fossa
olecranon, ulna
Anterior fossa
coronoid fossa, radius
Humerus
- Greater tubercle
- Lesser tubercle
- Head/neck
- Deltoid tuberosity
- Epicondyles
- Olecranon fossa
- Coronoid fossa
- Trochlea
- Capitulum
Femur
- Greater trochanter
- Lesser trochanter
- Head
- Neck
- Epicondyle
- Condyles
Knuckles
- Head of metacarpals
- Thumb 1, pinky 5
Ankle
- Calcaneus
- Talus
Autonomic nervous system
- Innervate smooth muscles, cardiac muscle, and glands
- Make adjustments to keep balance (homeostasis)
- Subconscious control
- Use a two neuron chain
- Preganglionic neuron soma from spinal cord ganglion gives signal to effector organs (cardiac/smooth muscle, glands, adipose tissue)
Central nervous system
- Brain
- Spinal cord
Peripheral nervous system
- Peripheral/spinal nerves (31)
- Cranial nerves (12)
- Autonomic nervous system (ANS) common sense
- Parasympathetic “rest and digest”
- Sympathetic “fight or flight”
Parasympathetic: (Ach)
- myelinated fast conduction
- ganglion Ach neurotransmitter
- nonmyelinated postganglionic axon
- long preganglionic Ach
- short postganglionic Ach
Sympathetic: (Ach/Norepinephrine)
- myelinated preganglionic axon Ach
- nonmyelinated postganglionic Norepinephrine
Adrenal Medulla
kidneys
- produces epinephrine/norepinephrine, releases them to blood
Dual innervation
- visceral organs needs both divisions
Differences/similarities of parasympathetic/sympathetic
- parasympathetic = craniosacral division
- sympathetic = thoracolumbar
*Effect is either stimulatory or inhibitory, depending on type of receptors
*Length of pre/post ganglionic axons
Special senses
- vision
- taste
- smell
- hearing
- equilibrium
Vision: dominant sense
- half of the cerebral cortex is involved in visual processing
- eyes sounded by fat protected by bone
- accessory structures: lacrimal apparatus
- extrinsic eye muscles
- conjunctiva
- sclera